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Chapter 7 Soft Tissue Response to Silicones

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Abstract

Although the term ’silicone’ refers to a group of organic silicone compounds, the one most commonly used in medicine is composed of a polymer known as dimethypolysiloxane (DMPS). In silicone gel the polymer is cross-linked; the more cross-linking, the more solid is the gel. Liquid silicone consists of glucose-linked DMPS polymer chains. Silicones first became commercially available in 1943, with the first subdermal implantation of silicone occurring in the late 1940s [1–3]. Silicones have since been developed for a wide variety of medical applications, most notably in joint and breast prostheses.

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Authors and Affiliations

  1. Division of Rheumatology Mayo Clinic, 200 First Street Southwest, Rochester, MN, 55905, USA

    S. E. Gabriel

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Editors and Affiliations

  1. Department of Biomedical Engineering and Department of Orthopedics and Rehabilitation, University of Wisconsin Department of Biomedical Engineering and, MADISON, Wisconsin, USA

    William Murphy

  2. King of Prussia, Principal: IMN Biomaterials King of Prussia, King of Prussia, PA, New York, USA

    Jonathan Black

  3. Staffordshire University (Emeritus), Lyme, Staffordshire, United Kingdom

    Garth Hastings

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Gabriel, S.E. (2016). Chapter 7 Soft Tissue Response to Silicones. In: Murphy, W., Black, J., Hastings, G. (eds) Handbook of Biomaterial Properties. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-3305-1_34

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