Metabolic and Endocrine Oncologic Emergencies

  • Sai-Ching J. YeungEmail author
  • Wenli Liu
Part of the MD Anderson Cancer Care Series book series (MDCCS)


Homeostatic regulation of key metabolites in cancer patients is often dysfunctional or perturbed by the malignancy or its treatment. Cancer and its treatment can also perturb the endocrine systems that regulate organ functions and metabolism. Deficiencies and excesses in electrolytes, metabolites, and hormones are discussed from the practical standpoint of acute clinical management in this chapter. Common etiologies and treatment approaches are also presented.


Hyponatremia Hypernatremia Hypokalemia Hyperkalemia Hypocalcemia Hypercalcemia Hypomagnesemia Hypermagnesemia Hypophosphatemia Hyperphosphatemia Hyperglycemia Hypoglycemia Adrenal crisis Hypothyroidism Hyperthyroidism Carcinoid crisis 

Suggested Readings

  1. Behl D, Hendrickson AW, Moynihan TJ. Oncologic emergencies. Crit Care Clin. 2010;26:181–205.CrossRefPubMedGoogle Scholar
  2. Glover DJ, Glick JH. Metabolic oncologic emergencies. CA Cancer J Clin. 1987;37:302–20.CrossRefPubMedGoogle Scholar
  3. Lewis MA, Hendrickson AW, Moynihan TJ. Oncologic emergencies: pathophysiology, presentation, diagnosis, and treatment. CA Cancer J Clin. 2011;61:287–314.PubMedGoogle Scholar
  4. Spinazze S, Schrijvers D. Metabolic emergencies. Crit Rev Oncol Hematol. 2006;58:79–89.CrossRefPubMedGoogle Scholar
  5. Taub YR, Wolford RW. Adrenal insufficiency and other adrenal oncologic emergencies. Emerg Med Clin North Am. 2009;27:271–82.CrossRefPubMedGoogle Scholar

Copyright information

© Springer Science+Business Media New York 2016

Authors and Affiliations

  1. 1.Departments of Emergency Medicine and Endocrine Neoplasia and Hormonal Disorders, Unit 1468The University of Texas MD Anderson Cancer CenterHoustonUSA
  2. 2.Department of General Internal MedicineThe University of Texas MD Anderson Cancer CenterHoustonUSA

Personalised recommendations