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HCV Recurrence: Predictors and Outcomes After Liver Transplantation

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Disease Recurrence After Liver Transplantation
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Abstract

In western countries, hepatitis C virus (HCV)-related end-stage cirrhosis represents the most frequent indication for liver transplantation (LT) (www.unos.org, www.eltr.org). Reinfection occurs invariably in those who are viremic at transplantation resulting in recurrent disease with uncertain outcome. Several factors, in particular, donor age, have shown to influence the natural history of HCV post-transplantation. Understanding which factors determine disease and patient outcomes, which modifications can be implemented to improve results, the feasibility of use and diagnostic reliability of available tools for monitoring disease evolution, and the place of retransplantation (RT) are still essential aspects in the setting of limited access to new antiviral drugs as well as for those failing new antiviral regimes.

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Rubín, A., Berenguer, M. (2016). HCV Recurrence: Predictors and Outcomes After Liver Transplantation. In: Thuluvath, P. (eds) Disease Recurrence After Liver Transplantation. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2947-4_3

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