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Pancreatic Advances

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Technological Advances in Surgery, Trauma and Critical Care

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Abstract

Over the past two decades, pancreas surgery has been associated with thorough research and investigation aimed at making significant improvements in the quality of surgical care delivered to patients. Decreasing inflammatory reactions, medical and endoscopic advances, and oncologic understanding of pancreatic neoplasms are some of the factors that have contributed significantly to these improvements. In this chapter, we focus on many of the advances seen in the preoperative, intraoperative, and postoperative setting that have led to a greater understanding of the care of patients who require surgical treatment for pancreatic disease. As understanding of pancreatic disease improves and as technology progresses, pancreas surgeons hope to continue to develop techniques that lead to better outcomes for patients.

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References

  1. McPhee JT, Hill JS, Whalen GF, Zayaruzny M, Litwin DE, Sullivan ME, et al. Perioperative mortality for pancreatectomy: a national perspective. Ann Surg. 2007;246(2):246–53.

    Article  PubMed Central  PubMed  Google Scholar 

  2. Tseng JF, Pisters PW, Lee JE, Wang H, Gomez HF, Sun CC, et al. The learning curve in pancreatic surgery. Surgery. 2007;141(4):456–63.

    Article  PubMed  Google Scholar 

  3. Pawlik TM, Laheru D, Hruban RH, Coleman J, Wolfgang CL, Campbell K, et al. Evaluating the impact of a single-day multidisciplinary clinic on the management of pancreatic cancer. Ann Surg Oncol. 2008;15(8):2081–8.

    Article  PubMed Central  PubMed  Google Scholar 

  4. Varadarajulu S, Eloubeidi MA. The role of endoscopic ultrasonography in the evaluation of pancreatico-biliary cancer. Surg Clin North Am. 2010;90(2):251–63.

    Article  PubMed  Google Scholar 

  5. Thosani N, Thosani S, Qiao W, Fleming JB, Bhutani MS, Guha S. Role of EUS-FNA-based cytology in the diagnosis of mucinous pancreatic cystic lesions: a systematic review and meta-analysis. Dig Dis Sci. 2010;55(10):2756–66.

    Article  PubMed Central  PubMed  Google Scholar 

  6. Papavasiliou P, Chun YS, Hoffman JP. How to define and manage borderline resectable pancreatic cancer. Surg Clin North Am. 2013;93(3):663–74.

    Article  PubMed  Google Scholar 

  7. Assifi MM, Lu X, Eibl G, Reber HA, Li G, Hines OJ. Neoadjuvant therapy in pancreatic adenocarcinoma: a meta-analysis of phase II trials. Surgery. 2011;150(3):466–73.

    Article  PubMed Central  PubMed  Google Scholar 

  8. Oliveira-Cunha M, Malde DJ, Aldouri A, Morris-Stiff G, Menon KV, Smith AM. Results of pancreatic surgery in the elderly: is age a barrier? HPB (Oxford). 2013;15(1):24–30.

    Article  Google Scholar 

  9. van der Gaag NA, Rauws EA, van Eijck CH, Bruno MJ, van der Harst E, Kubben FJ, et al. Preoperative biliary drainage for cancer of the head of the pancreas. N Engl J Med. 2010;362(2):129–37.

    Article  PubMed  Google Scholar 

  10. Tanaka M, Fernandez-del Castillo C, Adsay V, Chari S, Falconi M, Jang JY, et al. International consensus guidelines 2012 for the management of IPMN and MCN of the pancreas. Pancreatology. 2012;12(3):183–97.

    Article  PubMed  Google Scholar 

  11. Verbeke CS. Resection margins in pancreatic cancer. Surg Clin North Am. 2013;93(3):647–62.

    Article  PubMed  Google Scholar 

  12. Christians KK, Lal A, Pappas S, Quebbeman E, Evans DB. Portal vein resection. Surg Clin North Am. 2010;90(2):309–22.

    Article  PubMed  Google Scholar 

  13. Baumgartner JM, Krasinskas A, Daouadi M, Zureikat A, Marsh W, Lee K, et al. Distal pancreatectomy with en bloc celiac axis resection for locally advanced pancreatic adenocarcinoma following neoadjuvant therapy. J Gastrointest Surg. 2012;16(6):1152–9.

    Article  PubMed  Google Scholar 

  14. Pawlik TM, Gleisner AL, Cameron JL, Winter JM, Assumpcao L, Lillemoe KD, et al. Prognostic relevance of lymph node ratio following pancreaticoduodenectomy for pancreatic cancer. Surgery. 2007;141(5):610–8.

    Article  PubMed  Google Scholar 

  15. Kazanjian KK, Hines OJ, Duffy JP, Yoon DY, Cortina G, Reber HA. Improved survival following pancreaticoduodenectomy to treat adenocarcinoma of the pancreas: the influence of operative blood loss. Arch Surg. 2008;143(12):1166–71.

    Article  PubMed  Google Scholar 

  16. Yeh JJ, Gonen M, Tomlinson JS, Idrees K, Brennan MF, Fong Y. Effect of blood transfusion on outcome after pancreaticoduodenectomy for exocrine tumour of the pancreas. Br J Surg. 2007;94(4):466–72.

    Article  CAS  PubMed  Google Scholar 

  17. Mitchem JB, Hamilton N, Gao F, Hawkins WG, Linehan DC, Strasberg SM. Long-term results of resection of adenocarcinoma of the body and tail of the pancreas using radical antegrade modular pancreatosplenectomy procedure. J Am Coll Surg. 2012;214(1):46–52.

    Article  PubMed  Google Scholar 

  18. Stauffer JA, Nguyen JH, Heckman MG, Grewal MS, Dougherty M, Gill KR, et al. Patient outcomes after total pancreatectomy: a single centre contemporary experience. HPB (Oxford). 2009;11(6):483–92.

    Article  Google Scholar 

  19. Morgan K, Owczarski SM, Borckardt J, Madan A, Nishimura M, Adams DB. Pain control and quality of life after pancreatectomy with islet autotransplantation for chronic pancreatitis. J Gastrointest Surg. 2012;16(1):129–33. discussion 33–4.

    Article  PubMed  Google Scholar 

  20. Chauhan S, Forsmark CE. Pain management in chronic pancreatitis: a treatment algorithm. Best Pract Res Clin Gastroenterol. 2010;24(3):323–35.

    Article  PubMed  Google Scholar 

  21. Beger HG, Rau BM. New advances in pancreatic surgery. Curr Opin Gastroenterol. 2007;23(5):522–34.

    Article  PubMed  Google Scholar 

  22. Murage KP, Ball CG, Zyromski NJ, Nakeeb A, Ocampo C, Sandrasegaran K, et al. Clinical framework to guide operative decision making in disconnected left pancreatic remnant (DLPR) following acute or chronic pancreatitis. Surgery. 2010;148(4):847–56. discussion 56–7.

    Article  PubMed  Google Scholar 

  23. Lai EC, Lau SH, Lau WY. Measures to prevent pancreatic fistula after pancreatoduodenectomy: a comprehensive review. Arch Surg. 2009;144(11):1074–80.

    Article  PubMed  Google Scholar 

  24. Asbun HJ, Stauffer JA. Laparoscopic approach to distal and subtotal pancreatectomy: a clockwise technique. Surg Endosc. 2011;25(8):2643–9.

    Article  PubMed  Google Scholar 

  25. Shoup M, Brennan MF, McWhite K, Leung DH, Klimstra D, Conlon KC. The value of splenic preservation with distal pancreatectomy. Arch Surg. 2002;137(2):164–8.

    Article  PubMed  Google Scholar 

  26. Venkat R, Edil BH, Schulick RD, Lidor AO, Makary MA, Wolfgang CL. Laparoscopic distal pancreatectomy is associated with significantly less overall morbidity compared to the open technique: a systematic review and meta-analysis. Ann Surg. 2012;255(6):1048–59.

    Article  PubMed  Google Scholar 

  27. Tran Cao HS, Lopez N, Chang DC, Lowy AM, Bouvet M, Baumgartner JM, et al. Improved perioperative outcomes with minimally invasive distal pancreatectomy: results from a population-based analysis. JAMA Surg. 2014;149(3):237–43.

    Article  PubMed  Google Scholar 

  28. Stauffer JA, Rosales-Velderrain A, Goldberg RF, Bowers SP, Asbun HJ. Comparison of open with laparoscopic distal pancreatectomy: a single institution’s transition over a 7-year period. HPB (Oxford). 2013;15(2):149–55.

    Article  Google Scholar 

  29. Asbun HJ, Stauffer JA. Laparoscopic vs open pancreaticoduodenectomy: overall outcomes and severity of complications using the Accordion Severity Grading System. J Am Coll Surg. 2012;215(6):810–9.

    Article  PubMed  Google Scholar 

  30. van Santvoort HC, Besselink MG, Bakker OJ, Hofker HS, Boermeester MA, Dejong CH, et al. A step-up approach or open necrosectomy for necrotizing pancreatitis. N Engl J Med. 2010;362(16):1491–502.

    Article  PubMed  Google Scholar 

  31. Wente MN, Veit JA, Bassi C, Dervenis C, Fingerhut A, Gouma DJ, et al. Postpancreatectomy hemorrhage (PPH): an International Study Group of Pancreatic Surgery (ISGPS) definition. Surgery. 2007;142(1):20–5.

    Article  PubMed  Google Scholar 

  32. Wente MN, Bassi C, Dervenis C, Fingerhut A, Gouma DJ, Izbicki JR, et al. Delayed gastric emptying (DGE) after pancreatic surgery: a suggested definition by the International Study Group of Pancreatic Surgery (ISGPS). Surgery. 2007;142(5):761–8.

    Article  PubMed  Google Scholar 

  33. Bassi C, Dervenis C, Butturini G, Fingerhut A, Yeo C, Izbicki J, et al. Postoperative pancreatic fistula: an international study group (ISGPF) definition. Surgery. 2005;138(1):8–13.

    Article  PubMed  Google Scholar 

  34. Ghaferi AA, Birkmeyer JD, Dimick JB. Hospital volume and failure to rescue with high-risk surgery. Med Care. 2011;49(12):1076–81.

    Article  PubMed  Google Scholar 

  35. Buchler MW, Wagner M, Schmied BM, Uhl W, Friess H, Z’Graggen K. Changes in morbidity after pancreatic resection: toward the end of completion pancreatectomy. Arch Surg. 2003;138(12):1310–4. discussion 5.

    Article  PubMed  Google Scholar 

  36. Kennedy EP, Rosato EL, Sauter PK, Rosenberg LM, Doria C, Marino IR, et al. Initiation of a critical pathway for pancreaticoduodenectomy at an academic institution—the first step in multidisciplinary team building. J Am Coll Surg. 2007;204(5):917–23. discussion 23–4.

    Article  PubMed  Google Scholar 

  37. Kent TS, Sachs TE, Callery MP, Vollmer Jr CM. Readmission after major pancreatic resection: a necessary evil? J Am Coll Surg. 2011;213(4):515–23.

    Article  PubMed  Google Scholar 

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Author information

Authors and Affiliations

  1. Department of General Surgery, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL, 32224, USA

    John A. Stauffer & Horacio J. Asbun

Authors
  1. John A. Stauffer
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  2. Horacio J. Asbun
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Corresponding author

Correspondence to John A. Stauffer .

Editor information

Editors and Affiliations

  1. Department of Surgery, University of Arizona, Tucson, Arizona, USA

    Rifat Latifi

  2. Department of Surgery, The University of Arizona, Tucson, Arizona, USA

    Peter Rhee

  3. Department of Surgery, Professor of Surgery, Tucson, Arizona, USA

    Rainer W.G. Gruessner

Abbreviations

Abbreviations

BD-IPMN:

Branch duct intraductal papillary mucinous neoplasm

CT:

Computed tomography

DLPR:

Disconnected left pancreatic remnant

DP:

Distal pancreatectomy

ERCP:

Endoscopic retrograde cholangio-pancreatography

EUS:

Endoscopic ultrasonography

IPMN:

Intraductal papillary mucinous neoplasm

LNR:

Lymph node ratio

MCN:

Mucinous cystic neoplasms

MD-IPMN:

Main duct intraductal papillary mucinous neoplasm

MRCP:

Magnetic resonance cholangio-pancreatography

MRI:

Magnetic resonance imaging

N0:

Node negative

N1:

Node positive

PD:

Pancreaticoduodenectomy

PF:

Pancreatic fistula

R0:

Negative margin

R1:

Positive margin

RAMPS:

Radical antegrade modular pan-creatosplenectomy

TP:

Total pancreatectomy

TP-IAT:

Total pancreatectomy with islet autotransplantation

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Stauffer, J.A., Asbun, H.J. (2015). Pancreatic Advances. In: Latifi, R., Rhee, P., Gruessner, R. (eds) Technological Advances in Surgery, Trauma and Critical Care. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2671-8_36

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  • DOI: https://doi.org/10.1007/978-1-4939-2671-8_36

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-2670-1

  • Online ISBN: 978-1-4939-2671-8

  • eBook Packages: MedicineMedicine (R0)

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