Fungal Chemotaxonomy

  • Jens C. FrisvadEmail author
Part of the Fungal Biology book series (FUNGBIO)


MaSny chemotaxonomical methods have been suggested since the first chemical tests were used on basidiomycetes and lichens. Effective separation techniques, especially ultra-high performance liquid chromatography (UHPLC), and highly sensitive detection methods have been developed, especially mass spectrometric detection and diode array detection. Significant developments in biomolecular methods have made taxonomy and chemotaxonomy a rapidly developing field of science. Apart from DNA nucleotide sequences, the most studied molecules have been secondary metabolites (small molecule extrolites or natural products), and a large number of chemical studies have been made using profiles of extrolites, often in conjunction with fungal morphology, physiology, and molecular sequencing techniques, in a polyphasic approach to classification and identification. Species of filamentous fungi produce highly specific profiles of secondary metabolites, but the choice of growth and production media is very important to get as many extrolites expressed as possible. Many of these extrolites are promising drug lead candidates, or basis for other industrially usable compounds, making genomics and epigenetics important research fields in order to discover new biotechnological products.


Chemotaxonomy Secondary metabolites Extrolites Chromatography Spectrometry Growth media Filamentous fungi Penicillium Aspergillus 


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© Springer Science+Business Media New York 2015

Authors and Affiliations

  1. 1.Department of Systems BiologyTechnical University of DenmarkKongens LyngbyDenmark

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