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Topical Analgesic Medications

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Topical agents have become a commonly used treatment modality in chronic pain management. The use of these agents continues to grow, largely due to the increasing variety of medications available for topical use and their limited side effect profile. This chapter will address some of the more commonly used topical agents.


  • Chronic pain
  • Topical analgesics
  • Compounded topical agents
  • Diabetic peripheral neuropathy
  • Post-herpetic neuralgia
  • Complex regional pain syndrome
  • Neuropathic pain
  • Osteoarthritis
  • Capsaicin
  • Substance P
  • Local anesthetic
  • Lidocaine patch
  • Nonsteroidal anti-inflammatory drug
  • Methylsalicylate
  • Diclofenac
  • Doxepin
  • Dimethyl sulfoxide

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  • DOI: 10.1007/978-1-4939-2462-2_15
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Ca++ :



Complex regional pain syndrome


Dimethyl sulfoxide


Diabetic peripheral neuropathy


Eutectic mixture of local anesthetics


Food & Drug Administration


Glucose-6-phosphate dehydrogenase


Gamma amino butyric acid

Na+ :



N-methyl d-aspartate


Nonsteroidal anti-inflammatory drug


Post-herpetic neuralgia


Tricyclic antidepressant


Transient receptor potential


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Correspondence to Russell K. McAllister M.D., D.A.B.P.M. .

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McAllister, R.K., Burnett, C.J. (2015). Topical Analgesic Medications. In: Sackheim, K. (eds) Pain Management and Palliative Care. Springer, New York, NY.

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