Brain Tumors

  • Larry E. DavisEmail author
  • Sarah Pirio Richardson


This chapter begins with a discussion of common major clinical features and mechanisms of damage produced by brain tumors. Brain tumors are a collection of neoplasms of differing cell types, biology, prognosis, and treatment arising as a primary tumor or metastasis. Primary brain tumors in adults develop mainly above the tentorium while primary tumors develop in infants and children mainly in the posterior fossa. Most CNS tumors are of glial origin. Brain tumors produce signs and symptoms by three mechanisms: tumor location, tumor mass producing signs, and symptoms as it expands in a closed intracranial space, and finally the mass creating sufficient increased intracranial pressure to shift intracranial structures resulting in downward brain herniation. Brain tumors often cause cerebral edema with excess fluid either locally or diffusely in the brain. The cerebral edema can be vasogenic, cytotoxic, or interstitial. The chapter then discusses malignant glioma, meningioma, pituitary adenoma, and cerebral metastasis with attention to their pathophysiology, major clinical features, major laboratory findings, and principles of management and prognosis.


Glioma Meningioma Pituitary adenoma Cerebral metastasis Uncal herniation Tonsillar herniation Cerebral edema Vasogenic edema 

Recommended Reading

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Copyright information

© Springer Science+Business Media, LLC 2015

Authors and Affiliations

  1. 1.Chief Neurology ServiceDistinguished Professor of Neurology New Mexico VA Health Care SystemAlbuquerqueUSA
  2. 2.Department of Neurology Health Sciences CenterUniversity of New MexicoAlbuquerqueUSA

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