Preventing Pancreatic Fistula Following Distal Pancreatectomy

  • Bharath D. Nath
  • Mark P. CalleryEmail author


Pancreatic fistula is a common and highly morbid complication of distal pancreatectomy. Patient factors and technical factors appear to contribute to the incidence of postoperative pancreatic fistula (POPF). Numerous clinical trials and retrospective studies have investigated many of these with an aim toward identifying modifiable risk factors that could be controlled. Data on most of these risk factors remain relatively unconvincing. Careful surgical technique, ligation of the main duct, where technically feasible, and use of a mesh may be beneficial interventions. Octreotide and pancreatic duct stenting may have use in highly selected patient groups.


Distal pancreatectomy Stump leak Postoperative pancreatic fistula Pseudocyst Octreotide Pancreatic stent Minimally invasive pancreatectomy 


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  1. 1.Department of Surgery, Beth Israel Deaconess Medical CenterHarvard Medical SchoolBostonUSA

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