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The Science of Reconstructive Transplantation pp 33–44Cite as

Reconstructive Transplantation: What Can We Learn from Solid Organ Transplantation?

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Part of the book series: Stem Cell Biology and Regenerative Medicine ((STEMCELL))

Abstract

Reconstructive transplantation is a relatively new field with as-yet uncharted boundaries, while solid organ transplantation (SOT) has been developing for over half a century. Many technical, immunological, psychosocial, logistical, and legal solutions from SOT may be applied to vascularized composite allotransplantation (VCA). Other challenges are unique to VCA, including heightened immunogenicity, psychological identity changes, and the non-lifesaving nature of the graft. Nevertheless, clinical VCA owes its emergence to long-term refinement in SOT. The application of insights from each field to the other will continue to stimulate advancement in the future.

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Author information

Authors and Affiliations

  1. Department of Surgery, University of Maryland School of Medicine, 29 S. Greene Street, Suite 200, 21201, Baltimore, MD, USA

    Philip S. Brazio, Stephen T. Bartlett & Rolf N. Barth

  2. Department of Plastic Surgery, New York University School of Medicine, New York, NY, USA

    Eduardo D. Rodriguez

Authors
  1. Philip S. Brazio
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  2. Eduardo D. Rodriguez
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  4. Rolf N. Barth
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Corresponding author

Correspondence to Rolf N. Barth .

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Editors and Affiliations

  1. Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

    Gerald Brandacher

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Brazio, P., Rodriguez, E., Bartlett, S., Barth, R. (2015). Reconstructive Transplantation: What Can We Learn from Solid Organ Transplantation?. In: Brandacher, G. (eds) The Science of Reconstructive Transplantation. Stem Cell Biology and Regenerative Medicine. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-2071-6_3

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