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Migration and Communication Patterns in Skin Rejection

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The Science of Reconstructive Transplantation

Part of the book series: Stem Cell Biology and Regenerative Medicine ((STEMCELL))

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Abstract

Skin is the most immunogenic tissue of the human body. Its external location makes it the first barrier for invading pathogens and protects the individual from physical and chemical injury. In this chapter, we review skin immunology and its impact in reconstructive transplantation. The skin-resident immune system, mechanisms of leukocyte trafficking, the role of antigen-presenting cells, and potential tolerogenic mechanisms of the skin are highlighted in this chapter.

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Author information

Authors and Affiliations

  1. Center of Operative Medicine, Department of Visceral, Transplant and Thoracic Surgery, Innsbruck Medical University, Anichstrasse 35, 6020, Innsbruck, Austria

    Johanna Grahammer, Theresa Hautz, Johann Pratschke & Stefan Schneeberger

  2. Department of General, Visceral and Transplant Surgery, Charité, Berlin, Germany

    Johann Pratschke

  3. Department of Plastic and Reconstructive Surgery, The Johns Hopkins University School of Medicine, 720 Rutland Avenue, Baltimore, MD, USA

    Stefan Schneeberger

Authors
  1. Johanna Grahammer
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  2. Theresa Hautz
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  3. Johann Pratschke
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  4. Stefan Schneeberger
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Corresponding author

Correspondence to Johanna Grahammer .

Editor information

Editors and Affiliations

  1. Plastic and Reconstructive Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA

    Gerald Brandacher

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Grahammer, J., Hautz, T., Pratschke, J., Schneeberger, S. (2015). Migration and Communication Patterns in Skin Rejection. In: Brandacher, G. (eds) The Science of Reconstructive Transplantation. Stem Cell Biology and Regenerative Medicine. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-2071-6_11

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