TSH-Secreting Pituitary Adenoma

  • Abdulrahman Alkabbani
  • Roberto Salvatori
  • David S. Cooper


TSH-producing pituitary adenoma is a rare cause of thyrotoxicosis, and the rarest of all types of secretory pituitary adenomas. We present a case of a 55-year-old man who, after 6 years of therapy for presumed hypothyroidism, was diagnosed with a TSH-producing pituitary adenoma. He was lost to follow-up after that, to present again with thyrotoxicosis and atrial flutter 10 years later. We review the presentation, evaluation, treatment, and differential diagnosis of TSH-producing adenomas.


Thyrotoxicosis TSH-secreting adenoma Struma ovarii Exogenous thyrotoxicosis Thyroid gland TSH Free T4 


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Abdulrahman Alkabbani
    • 1
  • Roberto Salvatori
    • 1
  • David S. Cooper
    • 2
  1. 1.Division of Endocrinology and MetabolismJohns Hopkins HospitalBaltimoreUSA
  2. 2.Division of Endocrinology and MetabolismThe Johns Hopkins University School of MedicineBaltimoreUSA

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