Skip to main content
SpringerLink
Log in

Introduction, Evolution, and Application of the Van Nuys Prognostic Index in DCIS

  • Chapter
  • First Online:
Ductal Carcinoma In Situ and Microinvasive/Borderline Breast Cancer

  • 1206 Accesses

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
eBook
USD 16.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 159.00
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book
USD 109.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Silverstein MJ, Poller D, Craig P, et al. A prognostic index for ductal carcinoma in situ of the breast. Cancer. 1996;77:2267–74.

    Article  CAS  PubMed  Google Scholar 

  2. Silversten, MJ. The Univeristy of Southern California/Van Nuys prognostic index for ductal carcinoma in situ of the breast. Am J Surg. 2003;186:337–43.

    Article  Google Scholar 

  3. Sposto R, Epstein M, Silverstein MJ. Predicting local recurrence in patients with ductal carcinoma in situ of the breast. In: Silverstein MJ, Recht A, Lagios MD, editors. Ductal carcinoma in situ of the breast. Philadelphia: Williams and Wilkins; 2002. pp. 255–63.

    Google Scholar 

  4. Vicini F, Kestin L, Goldstein N, et al. Impact of young age on outcome in patients with ductal carcinoma-in-situ treated with breastconserving therapy. J Clin Oncol. 2000;18:296–306.

    CAS  PubMed  Google Scholar 

  5. Goldstein N, Vicini F, Kestin L, et al. Differences in the pathologic features of ductal carcinoma in situ of the breast based on patient age. Cancer. 2000;88:2552–60.

    Article  Google Scholar 

  6. MacAusland SG, Hepel JT, Chong FK, et al. An attempt to independently verify the utility of the Van Nuys prognostic index for ductal carcinoma in situ. Cancer. 2007;110:2648–53.

    Article  PubMed  Google Scholar 

  7. Di Saverio S, Catena F, Santini D, et al. 259 patients with DCIS of the breast applying USC/Van Nuys prognostic index: a retrospective review with long term follow up. Breast Cancer Res Treat. 2008;109:405–16.

    Article  PubMed  Google Scholar 

  8. Boland GP, Chan KC, Knox WF, et al. Value of the Van Nuys prognostic index in prediction of recurrence of ductal carcinoma in situ after breast-conserving surgery. Br J Surg. 2003;90:426–32.

    Article  CAS  PubMed  Google Scholar 

  9. Gilleard O, Goodman A, Cooper M, et al. The significance of the Van Nuys prognostic index in the management of ductal carcinoma in situ. World J Surg Oncol. 2008;6:61.

    Article  PubMed Central  PubMed  Google Scholar 

  10. Lee DY, Lewis JL, Wexelman BA, et al. The consequence of undertreatment of patients treated with breast conserving therapy for ductal carcinoma in situ. Am J Surg. 2013;206:790–7.

    Article  PubMed  Google Scholar 

  11. Fisher B, Costantino J, Redmond C, et al. Lumpectomy compared with lumpectomy and radiation therapy for the treatment of intraductal breast cancer. N Engl J Med. 1993;328:1581–6.

    Article  CAS  PubMed  Google Scholar 

  12. Carlson RW, Allred DC, Anderson BO, et al. NCCN clinical practice guidelines in oncology. Breast Cancer. 2008. www.nccn.org. 2008.

  13. Wehner P, Lagios M, Silverstein MJ. DCIS treated with excision alone using the national comprehensive cancer network (NCCN) guidelines. Ann Surg Oncol. 2013;20:3175–9.

    Article  PubMed  Google Scholar 

  14. Shah C, Julian T, Wikinson JB et al. Is ecision lone adequate for low risk DCIS of the breast treated with breast conserving therapy. J Radiat Oncol. 2014;3:21–8.

    Article  Google Scholar 

  15. Fisher B, Land S, Mamounas E et al. Prevention of invasive breast cancer in women with ductal carcinoma in situ: an update of the national surgical adjuvant breast and bowel project experience. Semin Oncol. 2001;28:400–18.

    Article  CAS  PubMed  Google Scholar 

  16. Bijker N, Meijnen P, Peterse JL et al. Breast-conserving treatment with or without radiotherapy in ductal carcinoma in-situ: ten-year results of the European organisation for research and treatment of cancer randomized phase III trial 10853—a study by the EORTC breast cancer cooperative group and EORTC radiotherapy group. J Clin Oncol. 2006;24:3381–7.

    Article  PubMed  Google Scholar 

  17. Holmberg L, Garmo H, Granstrand B et al. Absolute risk reduction for local recurrence after postoperative radiotherapy after sector resection for ductal carcinoma in situ of the breast. J Clin Oncol. 2008;26:1247–52.

    Article  PubMed  Google Scholar 

  18. Cuzick J, Sestak I, Pinder SE et al. Effect of tamoxifen and radiotherapy in women with locally excised ductal carcinoma in situ: long-term results from the UK/ANZ DCIS trial. Lancet Oncol. 2011;12:21–9.

    Article  CAS  PubMed  Google Scholar 

  19. Wapnir IL, Dignam JJ, Fisher B et al. Long-term outcomes of invasive ipsilateral breast tumor recurrences after lumpectomy in NSABP B-17 and B-24 randomized clinical trials for DCIS. J Natl Cancer Inst. 2011;103:478–88.

    Article  PubMed Central  PubMed  Google Scholar 

  20. Correa C, McGale P, Taylor C et al. Overview of the randomized trials of radiotherapy in ductal carcinoma in situ of the breast. J Natl Cancer Inst Monogr. 2010;2010:162–77.

    Article  CAS  PubMed  Google Scholar 

  21. Hughes LL, Wang M, Page DL et al. Local excision alone without irradiation for ductal carcinoma in situ of the breast: a trial of the Eastern cooperative oncology group. J Clin Oncol. 2009;27:5319–24.

    Article  PubMed Central  PubMed  Google Scholar 

  22. Solin L, Gray R, Baehner FL, et al. A quantitative multigene RTPCR assay for predicting recurrence risk after surgical excision alone without irradiation for ductal carcinoma in situ (DCIS): a prospective validation study of the DCIS score from ECOG E5194. 34th Annual San Antonio Breast Cancer Symposium. Abstract S4-6. 6–10 Dec 2011; San Antonio, Texas.

    Google Scholar 

  23. Wong JS, Kaelin CM, Troyan SL et al. Prospective study of wide excision alone for ductal carcinoma in situ of the breast. J Clin Oncol. 2006;24:1031–6.

    Article  PubMed  Google Scholar 

  24. McCormick B. RTOG 9804: a prospective randomized trial for “good risk” ductal carcinoma in situ (DCIS), comparing radiation (RT) to observation (OBS). J Clin Oncol. 2012;30(Suppl):1004.

    Google Scholar 

  25. Masson S, Bahl A. The Management of ductal carcinoma in situ: current controversies and future directions. Clin Oncol. 2013;25:275–82

    Article  CAS  Google Scholar 

  26. Badve SS, Gray RJ, Baehner FL et al. Correlation between the DCIS score and traditional clinicopathologic features in the prospectively designed E5194 clinical validation study. J Clin Oncol. 2012;30:1005.

    Article  Google Scholar 

  27. Altintas S, Toussaint J, Durbecq V, et al. Fine tuning of the Van Nuys prognostic index (VNPI) 2003 by integrating the genomic grade index (GGI): new tools for ductal carcinoma in situ (DCIS). Breast J. 2011;17(4):343e351.

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Division of Surgical Oncology, Department of Surgery, UT Southwestern Medical Center, 5323 Harry Hines Blvd., 75390-8548, Dallas, TX, USA

    Aeisha K. S. Rivers MD

Authors
  1. Aeisha K. S. Rivers MD
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Aeisha K. S. Rivers MD .

Editor information

Editors and Affiliations

  1. Comprehensive Cancer Center, University of Michigan Health System, Ann Arbor, Michigan, USA

    Lisa A. Newman

  2. Comprehensive Cancer Center, University of Michigan Health System, Ann Arbor, Michigan, USA

    Jessica M. Bensenhaver

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer Science+Business Media New York

About this chapter

Cite this chapter

Rivers, A. (2015). Introduction, Evolution, and Application of the Van Nuys Prognostic Index in DCIS. In: Newman, L., Bensenhaver, J. (eds) Ductal Carcinoma In Situ and Microinvasive/Borderline Breast Cancer. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2035-8_16

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-2035-8_16

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-2034-1

  • Online ISBN: 978-1-4939-2035-8

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics

Search

Navigation