Abstract
Microcystic adnexal carcinoma (MAC), first described by Goldstein et al. in 1982, represents a distinctive malignant neoplasm with an indolent, locally destructive behavior. The neoplasm has a predilection for the face and is composed of cornifying cystic structures in the upper portion, columnar and solid aggregations of pale or slightly dark eosinophilic epithelial cells in the middle, and duct-like or tubular structures in the lower part. The neoplasm manifests both sweat gland and follicular differentiation.
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Bibliography
Boos MD, Elenitsas R, Seykora J, et al. Benign subclinical syringomatous proliferations adjacent to a microcystic adnexal carcinoma: A tumor mimic with significant patient implications. Am J Dermatopathol 2014;36:174–8.
Chiller K, Passaro D, Scheuller M, et al. Microcystic adnexal carcinoma: forty-eight cases, their treatment, and their outcome. Arch Dermatol. 2000;136:1355–9.
Pujol RM, LeBoit PE, Su WP. Microcystic adnexal carcinoma with extensive sebaceous differentiation. Am J Dermatopathol. 1997;19:358–62.
Goldstein DJ, Barr RJ, Santa Cruz DJ. Microcystic adnexal carcinoma: a distinct clinicopathologic entity. Cancer. 1982;50:566–72.
Requena L, Kiryu H, Ackerman A, et al. Neoplasms with apocrine differentiation. Philadelphia: Lippincott-Raven; 1998.
Rongioletti F, Grosshans E, Rebora A. Microcystic adnexal carcinoma. Br J Dermatol. 1986;115:101–4.
Wick MR, Cooper PH, Swanson PE, et al. Microcystic adnexal carcinoma. An immunohistochemical comparison with other cutaneous appendage tumors. Arch Dermatol. 1990;126:189–94.
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Margaritescu, I., Chirita, A.D. (2015). Microcystic Adnexal Carcinoma. In: Rare Malignant Skin Tumors. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-2023-5_22
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DOI: https://doi.org/10.1007/978-1-4939-2023-5_22
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