Skip to main content

Chronic Pain Patients and Substance Abuse

  • Chapter
Substance Abuse

Abstract

The physical and mental states of human beings are governed by lifetime experiences and biopsychosocial makeup. They reinforce each other, and sometimes lead to maladaptive states, such as chronic pain, addiction, and so on. Pain and addiction are altered biopsychosocial experiences that are both subjective in nature and interact with one another. This interface of pain and addiction has brought about serious public health problems. It also poses ethical and healthcare dilemmas through the conflicting goals of managing pain states: pain relief, i.e. beneficence, and “do no harm”, i.e. nonmaleficence [Geppert C. To help and not to harm: ethical issues in the treatment of chronic pain in patients with substance use disorders. In: Clark MR, Treisman GJ, editors. Pain and depression. An interdisciplinary patient-centered approach. Adv Psychosom Med. Basel: Karger; 2004:25:151–71]. With the rise of medicinal management for chronic pain over the last two decades, addiction has become more prevalent, significantly increasing the risk of morbidity and mortality in this patient population. It is the responsibility of healthcare providers to utilize all the multimodal tools in their armamentarium to provide effective pain relief without unintentionally facilitating substance abuse.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 109.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 139.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Geppert C. To help and not to harm: ethical issues in the treatment of chronic pain in patients with substance use disorders. In Clark MR, Treisman GJ, editors. Pain and depression. An interdisciplinary patient-centered approach. Adv Psychosom Med. Karger: Basel; 2004;25:151–71.

    Google Scholar 

  2. Tsang A, Von Korff M, Lee S, et al. Common chronic pain conditions in developed and developing countries: gender and age differences and comorbidity with depression-anxiety disorders. J Pain. 2008;9(10):883–91.

    Article  PubMed  Google Scholar 

  3. Johannes CB, Le TK, Zhou X, Johnston JA, Dworkin RH. The prevalence of chronic pain in United States adults: results of an Internet-based survey. J Pain. 2010;11(11):1230–9.

    Article  PubMed  Google Scholar 

  4. Institute of Medicine Report from the Committee on Advancing Pain Research, Care, and Education. Relieving pain in America, a blueprint for transforming prevention, care, education and research. The National Academies Press; 2011.

    Google Scholar 

  5. Stewart WF, Ricci JA, Chee E, Morganstein D. Lost productive work time costs from health conditions in the United States: results from the American Productivity Audit. J Occup Environ Med. 2003;45(12):1234–46.

    Article  PubMed  Google Scholar 

  6. Results from the 2010 National Survey on Drug Use and Health: Summary of National Findings. http://www.oas.samhsa.gov/NSDUH/2k10NSDUH/2k10Results.pdf. Accessed Nov 2013.

  7. The Economic Impact of Illicit Drug Use on American Society. National Drug Intelligence Center. Washington, DC: United States Department of Justice; April 2011. http://www.simeoneassociates.com/assets/pdfs/SAI_Assessment1.pdf. Accessed Nov 2013.

  8. Substance Abuse and Mental Health Services Administration. Center for Behavioral Health Statistics and Quality. Drug abuse warning network, 2009: national estimates of drug-related emergency department visits; 2009. http://www.samhsa.gov/data/2k11/dawn/2k9dawned/html/dawn2k9ed.htm. Accessed Nov 2013.

  9. Substance Abuse and Mental Health Services Administration. Results from the 2011 National Survey on drug use and health: summary of national findings, NSDUH series H-44, HHS Publication No. SMA 12-4713. Rockville: Substance Abuse and Mental Health Services Administration; 2012. http://www.samhsa.gov/data/NSDUH/2k11Results/NSDUHresults2011.pdf. Accessed Nov 2013.

  10. Heimer R, Dasgupta N, Irwin KS, Kinzly M, Harvey AP, Givens A, Grau LE. Chronic pain, addiction severity, and misuse of opioids in Cumberland County, Maine. Addict Behav. 2011;37:346–9.

    Article  PubMed  Google Scholar 

  11. Fishbain DA, Cole B, Lewis J, Rosomoff HL, Rosomoff RS. What percentage of chronic nonmalignant pain patients exposed to chronic opioid analgesic therapy develop abuse/addiction and/or aberrant drug-related behaviors? A structured evidence-based review. Pain Med. 2008;9(4):444–59.

    Article  PubMed  Google Scholar 

  12. Rosenblum A, Joseph H, Fong C. Prevalence and characteristics of chronic pain among chemically dependent patients in methadone maintenance and residential treatment facilities. JAMA. 2003;289:2370–8.

    Article  PubMed  Google Scholar 

  13. Centers for Disease Control and Prevention. Vital signs: overdoses of prescription opioid pain relievers—United States, 1999–2008. MMWR Morb Mortal Wkly Rep. 2011;60(43):1487–92.

    Google Scholar 

  14. Warner M, Chen LH, Makuc DM, Anderson RN, Miniño AM. Drug poisoning deaths in the United States, 1980–2008. NCHS Data Brief # 81. December 2011.

    Google Scholar 

  15. http://www.cdc.gov/nchs/data/databriefs/db81.pdf. Accessed Nov 2013.

  16. Topics in brief: prescription drug abuse—December 2011: a research update from the National Institute on Drug Abuse. http://www.drugabuse.gov/publications/topics-in-brief/prescription-drug-abuse. Accessed Nov 2013.

  17. Gourlay D, Heit H, Almahrezi A. Universal precautions in pain medicine: a rational approach to the treatment of chronic pain. Pain Med. 2005;6(2):107–12.

    Article  PubMed  Google Scholar 

  18. Jamison RN, Serraillier J, Michna E. Assessment and treatment of abuse risk in opioid prescribing for chronic pain. Pain Res Treat. 2011;2011. Article ID 941808.

    Google Scholar 

  19. Moore TM, et al. A comparison of common screening methods for predicting aberrant behavior among patients receiving opioids for chronic pain management. Pain Med. 2009;10:1426–33.

    Article  PubMed  Google Scholar 

  20. Katz NP, Adamd EH, Benneyan JC, Birnbaum HG, Budman SH, Buzzeo RW, Carr DB, Cicero TJ, Gourlay D, Inciardi JA, Joranson DE, Kesslick J, Land SD. Foundations of opioid risk management. Clin J Pain. 2007;23:103–18.

    Article  PubMed  Google Scholar 

  21. Portenoy RK. Chronic opioid therapy in non-malignant pain. J Pain Symptom Manage. 1990;5:S46–62.

    Article  CAS  PubMed  Google Scholar 

  22. Owen GT, Burton AW, Schade CM, Passik S. Urine drug testing: current recommendations and best practices. Pain Physician. 2012;15:ES119–33.

    PubMed  Google Scholar 

  23. Hariharan J, Lamb GC, Neuner JM. Long-term opioid contract use for chronic pain management in primary care practice. A five year experience. J Gen Intern Med. 2007;22(4):485–90.

    Article  PubMed Central  PubMed  Google Scholar 

  24. Finklea KM, Bagalman E, Sacco LN. Prescription drug monitoring programs. http://ccc.healthcaredistribution.org/gov_affairs/pdf_misc/2012-08-20-crs_report.pdf. Accessed Nov 2013.

  25. Baehren DF, Marco CA, Droz DE, Sinha S, Callan EM, Akpunonu P. A statewide prescription monitoring program affects emergency department prescribing behaviors. Ann Emerg Med. 2010;56(1):19–23.

    Article  PubMed  Google Scholar 

  26. Guidance for industry format and content of proposed Risk Evaluation and Mitigation Strategies (REMS), REMS assessments, and proposed REMS modifications. http://www.fda.gov/downloads/Drugs/Guidances/UCM184128.pdf. Accessed Nov 2013.

  27. Extended-release (ER) and long-acting (LA) opioid analgesics risk evaluation and mitigation strategy (REMS). http://www.fda.gov/downloads/drugs/drugsafety/postmarketdrugsafetyinformationforpatientsandproviders/ucm311290.pdf. Accessed Nov 2013.

  28. Raffa RB, Pergolizzi Jr JV, Muñiz E, Taylor Jr R, Pergolizzi J. Designing opioids that deter abuse. Pain Res Treat. 2012;2012 [Epub 8 Nov 2012].

    Google Scholar 

  29. Laroche F, Rostaing S, Aubrun F, Perrot S. Pain management in heroin and cocaine users. Joint Bone Spine. 2012;79:446–50.

    Article  PubMed  Google Scholar 

  30. Passik SD, Kirsh KL. The interface between pain and drug abuse and the evolution of strategies to optimize pain management while minimizing drug abuse. Exp Clin Psychopharmacol. 2008;16(5):400–4.

    Article  PubMed  Google Scholar 

  31. American Psychiatric Association. Diagnostic and statistical manual of mental health disorders: DSM-5. 5th ed. Washington, DC: American Psychiatric Publishing; 2013.

    Google Scholar 

  32. Handelsman L, Cochrane KJ, Aronson MJ, Ness R, Rubinstein KJ, Kanof PD. Two new rating scales for opiate withdrawal. Am J Drug Alcohol Abuse. 1987;13(3):293–308.

    Article  CAS  PubMed  Google Scholar 

  33. Plunkett A, Kuehn D, Lenart M, Wilkinson I. Opioid maintenance, weaning and detoxification techniques: where we have been, where we are now and what the future holds. Pain Manage. 2013;3:277–84.

    Article  Google Scholar 

  34. Jones ES, Moore BA, Sindelar JL, O’Connor PG, Schottenfeld RS, Fiellin DA. Cost analysis of clinic and office-based treatment of opioid dependence: results with methadone and buprenorphine in clinically stable patients. Drug Alcohol Depend. 2009;99(1–3):132–40.

    Article  PubMed Central  PubMed  Google Scholar 

  35. Barry DT, Moore BA, Pantalon MV, Chawarski MC, Sillivan LE, O’Connor PG, Schottenfeld RS, Feillin DA. Patient satisfaction with primary care office-based buprinorphine/naloxone treatment. J Gen Intern Med. 2007;22(2):242–5.

    Article  PubMed Central  PubMed  Google Scholar 

  36. Fischer G, Gombas W, Eder H, Jagsch R, Paternell A, Stuhlinger G, Pezawas L, Aschauer HN, Kasper S. Buprenorphine versus methadone for treatment of opioid dependence. Addiction. 1999;94(9):1337–7.

    Article  CAS  PubMed  Google Scholar 

  37. Gowing L, Ali R, White JM. Opioid antagonists under heavy sedation or anaesthesia for opioid withdrawal. Cochrane Database Syst Rev. 2010;1, CD002022.

    PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Rahul Rastogi M.D. .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 Springer Science+Business Media New York

About this chapter

Cite this chapter

Rastogi, R., Narayanasamy, N., Sraow, P. (2015). Chronic Pain Patients and Substance Abuse. In: Kaye, A., Vadivelu, N., Urman, R. (eds) Substance Abuse. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1951-2_32

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-1951-2_32

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-1950-5

  • Online ISBN: 978-1-4939-1951-2

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics