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Branched Chain Amino Acids in Chronic Obstructive Pulmonary Disease

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Abstract

Chronic obstructive pulmonary disease (COPD) is characterized by persistent airflow limitation that is usually progressive. COPD patients have dyspnea, chronic cough and sputum production. In addition, patients with COPD develop systemic features such as body weight (BW) loss, especially muscle wasting, and skeletal muscle dysfunction in addition to pulmonary impairment. Several studies have reported decreased branched-chain amino acids (BCAA) concentration in the plasma and skeletal muscles of depleted patients with COPD. Reduced levels of BCAA may affect muscle energy metabolism during exercise. Some investigations showed that nutritional support with essential amino acids containing high BCAA produced good results in patients with COPD. Nutritional support for pulmonary rehabilitation is needed in COPD patients. Further study is needed to determine prescription nutritional support.

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Correspondence to Tomoko Kutsuzawa M.D., Ph.D. .

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© 2015 Springer Science+Business Media New York

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Kutsuzawa, T., Haida, M. (2015). Branched Chain Amino Acids in Chronic Obstructive Pulmonary Disease. In: Rajendram, R., Preedy, V., Patel, V. (eds) Branched Chain Amino Acids in Clinical Nutrition. Nutrition and Health. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-1914-7_10

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  • DOI: https://doi.org/10.1007/978-1-4939-1914-7_10

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-1913-0

  • Online ISBN: 978-1-4939-1914-7

  • eBook Packages: MedicineMedicine (R0)

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