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The Influence of Pain on Reward Processing: Current Literature and Prospects

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Neurobiological Studies of Addiction in Chronic Pain States

Part of the book series: Contemporary Clinical Neuroscience ((CCNE,volume 17))

Abstract

Both short- and long-term pain influence reward processing. Albeit the literature is still scarce, a picture is emerging in which pain increases the motivational drive to obtain reward, whereas the pleasure that is felt when a reward is obtained seems to be unchanged or even decreased. In addition, brain systems that are important for pain modulation as well as reward processing are altered by pain, possibly leading to less efficient endogenous pain control and contributing to emotional sequelae of chronic pain. Altered reward processing, including increased motivational drive and urge, and increased pain sensitivity might contribute to problematic drug behaviors in some chronic pain patients.

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Authors and Affiliations

  1. Alan Edwards Centre for Research on Pain (AECRP), McGill University, Montreal, QC, Canada, H3A 1A4

    Wiebke Gandhi, Susanne Becker Ph.D. & Petra Schweinhardt M.D., Ph.D.

  2. Faculty of Dentistry, McGill University, Montreal, QC, Canada, H3A 2B2

    Wiebke Gandhi, Susanne Becker Ph.D. & Petra Schweinhardt M.D., Ph.D.

Authors
  1. Wiebke Gandhi
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  2. Susanne Becker Ph.D.
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  3. Petra Schweinhardt M.D., Ph.D.
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Correspondence to Petra Schweinhardt M.D., Ph.D. .

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Editors and Affiliations

  1. Departments of Pharmaceutics, Pharmacology, Neuroscience, University of Minnesota, Minneapolis, Minnesota, USA

    Carolyn A. Fairbanks

  2. Pain Mechanisms Laboratory, Department of Anesthesiology, Wake Forest University Health Sciences, Winston-Salem, North Carolina, USA

    Thomas J. Martin, Ph.D.

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Gandhi, W., Becker, S., Schweinhardt, P. (2014). The Influence of Pain on Reward Processing: Current Literature and Prospects. In: Fairbanks, C., Martin, Ph.D., T. (eds) Neurobiological Studies of Addiction in Chronic Pain States. Contemporary Clinical Neuroscience, vol 17. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1856-0_3

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