Skip to main content

Abstract

Discography was introduced in the 1940s to diagnose herniation and internal annular disruption of the lumbar and subsequently cervical and thoracic intervertebral discs. While the development of CT and MRI scans unquestionably provides the physician with invaluable information, discography combined with a CT scan remains the most accurate method of detailing internal annular disruption and disc morphology. Unlike noninvasive imaging tests, pressurizing the disc adds critical information if significant; concordant pain is reproduced; and more importantly, a negative response to provocation discography assists in identifying negative discs for which surgery is not recommended. Theoretically, speed- and pressure-controlled injection of contrast media into the disc nucleus stimulates nerve endings via two mechanisms: a chemical stimulus from contact between contrast dye and sensitized nociceptors and a mechanical stimulus resulting from the fluid-distending stress simulating loading.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 169.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

References

  1. Lindblom K. Technique and results in myelography and disc puncture. Acta Radiol. 1950;34:321–30.

    Article  CAS  PubMed  Google Scholar 

  2. Lindblom K. Technique and results of diagnostic disc puncture and injection (discography) in the lumbar region. Acta Orthop Scand. 1951;20:315–26.

    Article  CAS  PubMed  Google Scholar 

  3. Guyer RD, Ohnmeiss DD. Lumbar discography. Position statement from the North American Spine Society Diagnostic and Therapeutic Committee. Spine. 1995;20:2048–59.

    Article  CAS  PubMed  Google Scholar 

  4. O’Neill C, Derby R. Percutaneous discectomy using nucleoplasty. In: International 21st course for percutaneous endoscopic spinal surgery and complementary techniques. Spital zolikerberg, Zurich; 2003.

    Google Scholar 

  5. Bogduk N, Tynan W, Wilson AS. The nerve supply to the human lumbar intervertebral discs. J Anat. 1981;132:39–56.

    CAS  PubMed Central  PubMed  Google Scholar 

  6. Yoshizawa H, O’Brien JP, Smith WT, Trumper M. The neuropathology of intervertebral discs removed for low-back pain. J Pathol. 1980;132:95–104.

    Article  CAS  PubMed  Google Scholar 

  7. Groen GJ, Baljet B, Drukker J. Nerves and nerve plexuses of the human vertebral column. Am J Anat. 1990;188:282–96.

    Article  CAS  PubMed  Google Scholar 

  8. Malinsky J. The ontogenetic development of nerve terminations in the intervertebral discs of man. (Histology of intervertebral discs, 11th communication). Acta Anat (Basel). 1959;38:96–113.

    Article  CAS  Google Scholar 

  9. Weinstein J, Claverie W, Gibson S. The pain of discography. Spine (Phila Pa 1976). 1988;13:1344–8.

    Article  CAS  Google Scholar 

  10. Korkala O, Gronblad M, Liesi P, Karaharju E. Immunohistochemical demonstration of nociceptors in the ligamentous structures of the lumbar spine. Spine. 1985;10:156–7.

    Article  CAS  PubMed  Google Scholar 

  11. Konttinen YT, et al. Neuroimmunohistochemical analysis of peridiscal nociceptive neural elements. Spine (Phila Pa 1976). 1990;15:383–6.

    Article  CAS  Google Scholar 

  12. Peng B, et al. The pathogenesis of discogenic low back pain. J Bone Joint Surg. 2005;87:62–7.

    CAS  Google Scholar 

  13. Freemont AJ, et al. Nerve ingrowth into diseased intervertebral disc in chronic back pain. Lancet. 1997;350:178–81.

    Article  CAS  PubMed  Google Scholar 

  14. Coppes MH, Marani E, Thomeer RT, Groen GJ. Innervation of “painful” lumbar discs. Spine. 1997;22:2342–9; discussion 2349–50.

    Article  CAS  PubMed  Google Scholar 

  15. Bogduk N, Aprill C, Derby R, et al. Discography. In: Spine care: diagnosis and conservative treatment. St. Louis: Mosby; 1995. p. 219–36.

    Google Scholar 

  16. Moneta GB, et al. Reported pain during lumbar discography as a function of annular ruptures and disc degeneration. A re-analysis of 833 discograms. Spine (Phila Pa 1976). 1994;19:1968–74.

    Article  CAS  Google Scholar 

  17. Vanharanta H, et al. The relationship of pain provocation to lumbar disc deterioration as seen by CT/discography. Spine. 1987;12:295–8.

    Article  CAS  PubMed  Google Scholar 

  18. Greenspan A, Amparo EG, Gorczyca DP, Montesano PX. Is there a role for diskography in the era of magnetic resonance imaging? Prospective correlation and quantitative analysis of computed tomography-diskography, magnetic resonance imaging, and surgical findings. J Spinal Disord. 1992;5:26–31.

    Article  CAS  PubMed  Google Scholar 

  19. Carragee EJ, et al. Does discography cause accelerated progression of degeneration changes in the lumbar disc: a ten-year matched cohort study. Spine (Phila Pa 1976). 2009;34:2338–45.

    Article  Google Scholar 

  20. Wolfer LR, Derby R, Lee J-E, Lee S-H. Systematic review of lumbar provocation discography in asymptomatic subjects with a meta-analysis of false-positive rates. Pain Physician. 2008;11:513–38.

    PubMed  Google Scholar 

  21. Bogduk N. Proposed discography standards. ISIS newsletter. Daly City: International Spinal Injection Society; 1994. p. 10–3.

    Google Scholar 

  22. Derby R. A second proposal for discography standards. ISIS newsletter. Daly City: International Spinal Injection Society; 1994. p. 108–22.

    Google Scholar 

  23. Jensen MC, et al. Magnetic resonance imaging of the lumbar spine in people without back pain. N Engl J Med. 1994;331:69–73.

    Article  CAS  PubMed  Google Scholar 

  24. Carragee EJ, et al. The rates of false-positive lumbar discography in select patients without low back symptoms. Spine. 2000;25:1373–80. discussion 1381.

    Article  CAS  PubMed  Google Scholar 

  25. Fraser RD, Osti OL, Vernon-Roberts B. Discitis after discography. J Bone Joint Surg Br. 1987;69:26–35.

    CAS  PubMed  Google Scholar 

  26. Fraser RD, Osti OL, Vernon-Roberts B. Iatrogenic discitis: the role of intravenous antibiotics in prevention and treatment. An experimental study. Spine. 1989;14:1025–32.

    Article  CAS  PubMed  Google Scholar 

  27. Polk HC, Christmas AB. Prophylactic antibiotics in surgery and surgical wound infections. Am Surg. 2000;66:105–11.

    PubMed  Google Scholar 

  28. Osti OL, Fraser RD, Vernon-Roberts B. Discitis after discography. The role of prophylactic antibiotics. J Bone Joint Surg Br. 1990;72:271–4.

    CAS  PubMed  Google Scholar 

  29. Troiser O. Technique de la discographie extra-durale. J Radiol. 1982;63:571–8.

    Google Scholar 

  30. Aprill III C. Diagnostic disc injection. In: Frymoyer JW, editor. The adults spine: principles and practice. 2nd ed. Philadelphia: Lippincott-Raven; 1996.

    Google Scholar 

  31. Milette PC, Melanson D. A reappraisal of lumbar discography. J Can Assoc Radiol. 1982;33:176–82.

    CAS  PubMed  Google Scholar 

  32. Bogduk N. Practice guidelines for spinal diagnostic and treatment procedures. San Francisco: International Spine Intervention Society; 2004.

    Google Scholar 

  33. Adams MA, Dolan P, Hutton WC. The stages of disc degeneration as revealed by discograms. J Bone Joint Surg Br. 1986;68:36–41.

    CAS  PubMed  Google Scholar 

  34. Bogduk NC, April C, Derby R, et al. Discography. In: White A, editor. Spine care. Diagnosis and conservative treatment. St. Louis: Mosby Co; 1995. p. 219–36.

    Google Scholar 

  35. Derby R, Kim B-J, Chen Y, Seo K-S, Lee S-H. The relation between annular disruption on computed tomography scan and pressure-controlled diskography. Arch Phys Med Rehabil. 2005;86:1534–8.

    Article  PubMed  Google Scholar 

  36. Aprill C, Bogduk N. High-intensity zone: a diagnostic sign of painful lumbar disc on magnetic resonance imaging. Br J Radiol. 1992;65:361–9.

    Article  CAS  PubMed  Google Scholar 

  37. Sachs BL, et al. Dallas discogram description. A new classification of CT/discography in low-back disorders. Spine. 1987;12:287–94.

    Article  CAS  PubMed  Google Scholar 

  38. Derby R. Lumbar discometry. Sci Newsl Int Spine Injection Soc Newsl. 1993;1:8–17.

    Google Scholar 

  39. Derby R, et al. The ability of pressure-controlled discography to predict surgical and nonsurgical outcomes. Spine. 1999;24:364–71; discussion 371–62.

    Article  CAS  PubMed  Google Scholar 

  40. Carragee EJ, Tanner CM, Yang B, Brito JL, Truong T. False-positive findings on lumbar discography. Reliability of subjective concordance assessment during provocative disc injection. Spine. 1999;24:2542–7.

    Article  CAS  PubMed  Google Scholar 

  41. Derby R, Lee SH, Kim BJ. Discography. In: Slipman CW, Derby R, Simeone FA, Mayer TG, editors. Interventional spine: an algorithmic approach. Philadelphia: Saunders Elsevier; 2008. p. 291–302.

    Google Scholar 

  42. Seo K-S, et al. In vitro measurement of pressure differences using manometry at various injection speeds during discography. Spine J. 2007;7:68–73.

    Article  PubMed  Google Scholar 

  43. Singh V. The role of cervical discography in interventional pain management. Pain Physician. 2004;7:249–55.

    PubMed  Google Scholar 

  44. Connor P, Darden BV. Cervical discography complications and clinical efficacy. Spine. 1993;18:2035.

    Article  CAS  PubMed  Google Scholar 

  45. Manchikanti L, et al. Systematic review of cervical discography as a diagnostic test for chronic spinal pain. Pain Physician. 2009;12:305–21.

    PubMed  Google Scholar 

  46. Derby R, Melfi R, Talu G, Aprill C. Cervical discography: diagnostic value and complications. In: Curtis W, Slipman CW, Derby R, Simeone FA, Mayer TG, editors. Interventional spine: an algorithmic approach. New York: Saunders Publishers; 2007.

    Google Scholar 

  47. Schellhas KP, Smith MD, Gundry CR, Pollei SR. Cervical discogenic pain. Prospective correlation of magnetic resonance imaging and discography in asymptomatic subjects and pain sufferers. Spine. 1996;21:300–11.

    Article  CAS  PubMed  Google Scholar 

  48. Bogduk N, Aprill C. On the nature of neck pain, discography and cervical zygapophysial joint blocks. Pain. 1993;54:213–7.

    Article  CAS  PubMed  Google Scholar 

  49. Schellhas K, Pollei SR, Dorwart R. Thoracic discography. A safe and reliable technique. Spine. 1994;19:2103–9.

    Article  CAS  PubMed  Google Scholar 

  50. Thomas PS. Image-guided pain management. Philadelphia: Lippincott-Raven; 1997.

    Google Scholar 

  51. Vanharanta H, et al. Pain provocation and disc deterioration by age. A CT/discography study in a low-back pain population. Spine. 1989;14:420–3.

    Article  CAS  PubMed  Google Scholar 

  52. Tsuji N, Igarashi S, Koyama T. Spinal epidural abscess – report of 5 cases. No Shinkei Geka. 1987;15:1079–85.

    CAS  PubMed  Google Scholar 

  53. Junila J, Niinimaki T, Tervonen O. Epidural abscess after lumbar discography. A case report. Spine. 1997;22:2191–3.

    Article  CAS  PubMed  Google Scholar 

  54. Baker AS, Ojemann RG, Swartz MN, Richardson EP. Spinal epidural abscess. N Engl J Med. 1975;293:463–8.

    Article  CAS  PubMed  Google Scholar 

  55. Ravicovitch MA, Spallone A. Spinal epidural abscesses. Surgical and parasurgical management. Eur Neurol. 1982;21:347–57.

    Article  CAS  PubMed  Google Scholar 

  56. Lownie SP, Ferguson GG. Spinal subdural empyema complicating cervical discography. Spine. 1989;14:1415–7.

    Article  CAS  PubMed  Google Scholar 

  57. Guyer RD, et al. Discitis after discography. Spine. 1988;13:1352–4.

    Article  CAS  PubMed  Google Scholar 

  58. Roosen K, Bettag W, Fiebach O. Complications of cervical discography(author’s transl). ROFO Fortschr Geb Rontgenstr Nuklearmed. 1975;122:520–7.

    Article  CAS  PubMed  Google Scholar 

  59. Vogelsang H. Cervical intervertebral discitis after discography (author’s transl). Neurochirurgia (Stuttg). 1973;16:80–3.

    CAS  Google Scholar 

  60. Brodsky AE, Binder WF. Lumbar discography. Its value in diagnosis and treatment of lumbar disc lesions. Spine. 1979;4:110–20.

    Article  CAS  PubMed  Google Scholar 

  61. Johnson G. Traumatic pneumothorax: is a chest drain always necessary? J Accid Emerg Med. 1996;13:173–4.

    Article  CAS  PubMed Central  PubMed  Google Scholar 

  62. Carragee EJ. Prevalence and clinical features of internal disk disruption in patients with chronic low back pain. Spine. 1996;21:776–7.

    Article  CAS  PubMed  Google Scholar 

  63. Derby R, Guyer R, Lee SH, Seo KS, Chen Y. The rational use and limitations of provocative discography. International Spine Intervention Society 13th annual meeting in NY, ISIS Newsletter. 2004;5:6–20.

    Google Scholar 

  64. Derby R, et al. Comparison of discographic findings in asymptomatic subject discs and the negative discs of chronic LBP patients: can discography distinguish asymptomatic discs among morphologically abnormal discs? Spine J. 2005;5:389–94.

    Article  PubMed  Google Scholar 

  65. Shin D, Kim H, Jung J, Sin D, Lee J. Diagnostic relevance of pressure-controlled discography. J Korean Med Sci. 2006;21:911–6.

    Article  PubMed Central  PubMed  Google Scholar 

  66. Manchikanti L, et al. Provocative discography in low back pain patients with or without somatization disorder: a randomized prospective evaluation. Pain Physician. 2001;4:227–39.

    CAS  PubMed  Google Scholar 

  67. Derby R, et al. The influence of psychologic factors on diskography in patients with chronic axial low back pain. Arch Phys Med Rehabil. 2008;89:1300–4.

    Article  PubMed  Google Scholar 

  68. Derby R, Wolfer L, Summers J. Does discography cause accelerated progression of degeneration in the lumbar spine. SpineLine. 2010:Mar/Apr:26–30.

    Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Richard Derby M.D. .

Editor information

Editors and Affiliations

Rights and permissions

Reprints and permissions

Copyright information

© 2015 American Academy of Pain Medicine

About this chapter

Cite this chapter

Melnik, I., Derby, R., Baker, R.M. (2015). Provocative Discography. In: Deer, T., Leong, M., Buvanendran, A., Kim, P., Panchal, S. (eds) Treatment of Chronic Pain by Interventional Approaches. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1824-9_26

Download citation

  • DOI: https://doi.org/10.1007/978-1-4939-1824-9_26

  • Published:

  • Publisher Name: Springer, New York, NY

  • Print ISBN: 978-1-4939-1823-2

  • Online ISBN: 978-1-4939-1824-9

  • eBook Packages: MedicineMedicine (R0)

Publish with us

Policies and ethics