Fibrous/Myofibroblastic Proliferations of the Vulva

  • Cesar A. Llanos
  • Andrew E. RosenbergEmail author


Mesenchymal tumors of the vulva are relatively uncommon. The majority is benign and composed of cells that demonstrate fibroblastic and myofibroblastic differentiation admixed with other connective tissue stromal elements. Many of the tumors are restricted to the distal superficial portion of the gynecological tract and have distinctive morphological features. Immunohistochemistry and molecular analyses are helpful in accurately identifying these tumors in select circumstances. The correct diagnosis is of importance as some of these various tumors have very different clinical outcomes.


Vulva Fibrous Myofibroblastic Fibroepithelial polyp Vulvar edema Prepubertal Fibroma Angiofibroma Angiomyofibroblastoma Aggressive angiomyxoma Myofibroblastoma Reactive proliferation Postoperative spindle cell nodule 


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  1. 1.Department of Pathology, Miller School of MedicineUniversity of MiamiMiamiUSA
  2. 2.Department of PathologyUniversity of Miami HospitalMiamiUSA

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