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Optical Coherence Tomography of Malignancies of the Head and Neck

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Biomedical Optics in Otorhinolaryngology

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Abstract

Optical coherence tomography (OCT) is a minimally invasive optical imaging modality which produces high-resolution, three-dimensional (3D) images of biological tissue. In the last 10 years, biophotonics and optics research have led to the advancement of OCT technology and expansion of OCT applications within Otorhinolaryngology—Head and Neck Surgery. In vivo clinical studies have demonstrated the potential for OCT to perform minimally invasive diagnostic imaging and differentiation of premalignant and malignant lesions of the head and neck. This chapter reviews the research and clinical applications for OCT imaging of malignancy in the upper aerodigestive tract.

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Author information

Authors and Affiliations

  1. Department of Otolaryngology—Head and Neck Surgery, UC Irvine Medical Center, Orange, CA, USA

    Giriraj K. Sharma MD, MS

  2. The Beckman Laser Institute, Department of Otorhinolaryngology, Klinikum der Universität München, Munich, Germany

    Marc Rubinstein

  3. The Beckman Laser Institute, Dept of Oto, Munich, Irvine, CA, USA

    Brian J.-F. Wong MD, PhD

  4. Department of Otorhinolaryngolog, Munich University Hospital, Munich, 81377, USA

    Christian Betz MD

Authors
  1. Giriraj K. Sharma MD, MS
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  2. Marc Rubinstein
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  3. Christian Betz MD
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  4. Brian J.-F. Wong MD, PhD
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Corresponding author

Correspondence to Brian J.-F. Wong MD, PhD .

Editor information

Editors and Affiliations

  1. Department of Otolaryngology Head and Neck Surgery, Department of Biomedical Engineering, Division of Facial Plastic Surgery, The Beckman Laser Institute and Medical Clinic, University of California Irvine, Irvine, California, USA

    Brian J.-F. Wong

  2. Department of Otorhinolaryngology, Plastic, Head and Neck Surgery, RWTH Aachen University Hospital, Aachen, Germany

    Justus Ilgner

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Sharma, G.K., Rubinstein, M., Betz, C., Wong, B.JF. (2016). Optical Coherence Tomography of Malignancies of the Head and Neck. In: Wong, BF., Ilgner, J. (eds) Biomedical Optics in Otorhinolaryngology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1758-7_36

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  • DOI: https://doi.org/10.1007/978-1-4939-1758-7_36

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