Malignant Renal Tumors

  • Bahig M. Shehata
  • Mina M. Naguib
  • Jenny Lin
  • Geetika Khanna


The majority of pediatric renal tumors are Wilms’ tumors. Of particular concern are those renal neoplasms carrying malignant potential. These entities are given particular attention in this chapter. Universally, partial and radical nephrectomies are used to treat both benign and malignant neoplasms. Chemotherapies have improved the prognosis of many malignant renal tumors, such as Wilms, but others, especially those carrying INI-1 mutations, remain difficult to treat and have high mortality rates. More molecular and genetic research is needed to fully understand and successfully treat this subset of childhood tumor.


Wilms’ tumor Pediatric Neoplasms Kidney Renal Nephroblastomatosis Nephrogenic rests Cystic nephroma Congenital mesoblastic nephroma Clear cell sarcoma of the kidney Rhabdoid tumor Renal cell carcinomas Renal medullary carcinoma 


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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • Bahig M. Shehata
    • 2
  • Mina M. Naguib
    • 2
  • Jenny Lin
    • 2
  • Geetika Khanna
    • 1
  1. 1.Radiology, St. Louis Children’s HospitalWashington University School of Medicine – MIRSt. LouisUSA
  2. 2.Department of Pathology and PediatricsEmory University School of Medicine, Pediatric Pathologist, Children’s Healthcare of AtlantaAtlantaUSA

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