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Well-Differentiated Malignancies pp 45–65Cite as

The Genitourinary System

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Part of the book series: Current Clinical Pathology ((CCPATH))

Abstract

The normal renal parenchyma is composed of tightly packed tubules and glomeruli which are delimited by a capsule. The tubules are situated on a thin basement membrane which is supported by a complex network of specialized interstitial fibroblasts [1, 2]. The interstitial cells also play important roles in the modulation of hemodynamic tubular reabsorption and erythropoietin production. There are at least two types of cortical interstitial cells and three types of medullary interstitial cells to accommodate the normal function of the organ. Importantly, the type 1 medullary interstitial cells are characterized by their prominent lipid storage capabilities and peroxidase activity.

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Authors and Affiliations

  1. Department of Pathology Beckley Veterans Medical Center (West Virginia), McGuire Veterans Medical Center, Virginia Commonwealth University, Richmond, VA, USA

    Xichun Sun M.D, Ph.D. (Medical Director, Staff Pathologist, Assistant Professor)

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  1. Xichun Sun M.D, Ph.D.
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Sun, X. (2015). The Genitourinary System. In: Well-Differentiated Malignancies. Current Clinical Pathology. Humana Press, New York, NY. https://doi.org/10.1007/978-1-4939-1692-4_5

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  • DOI: https://doi.org/10.1007/978-1-4939-1692-4_5

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  • Publisher Name: Humana Press, New York, NY

  • Print ISBN: 978-1-4939-1691-7

  • Online ISBN: 978-1-4939-1692-4

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