Abstract
Systemic lupus erythematosus (SLE) is a multiorgan autoimmune disease arising from dysregulation in the immune system. The disease process begins when a genetically susceptible individual is exposed to an environmental trigger, i.e., infection, which in turn triggers the process of antinuclear antibody production. This process starts the deposit of immune complex materials in various organs that can initiate an inflammatory process. Furthermore, B- and T-cell abnormal signaling promotes this immune activation.
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Famorca, L., O’Neill, J. (2015). Connective Tissue Disease. In: O'Neill, J. (eds) Essential Imaging in Rheumatology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1673-3_7
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DOI: https://doi.org/10.1007/978-1-4939-1673-3_7
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