Abstract
Immunohistochemistry is a multistep pathology-based diagnostic tool that allows the visualization and identification in situ of specific cellular antigens that may be altered in response to a disease process or exposure to a toxicant. The technique is now well established and continually evolving for routine and research use, for clinical diagnosis, and in a toxicologic pathology laboratory. While quality control guidelines have been recommended for assays in clinical use, similar guidelines remain to be established for a toxicological pathology laboratory.
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Aziz, S.A., Mehta, R. (2016). Immunohistochemistry: Overview, Its Potential, and Challenges. In: Aziz, S., Mehta, R. (eds) Technical Aspects of Toxicological Immunohistochemistry. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1516-3_1
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DOI: https://doi.org/10.1007/978-1-4939-1516-3_1
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