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Implants as Sustained Release Delivery Devices for Vaccine Antigens

Part of the Advances in Delivery Science and Technology book series (ADST)

Abstract

The focus of this chapter will be on implantable devices for the purpose of vaccine delivery. This area of research has not yet been fully explored, but the most recent literature will be summarized. The chapter will provide some background and historical information on implants. In addition, different ways of manufacturing implants, from small lab-scale to potential large-scale production, will be described. Characterization of the implants will be discussed, with a focus on antigen release as well as degradation/erosion processes. Preclinical studies for assessment of biocompatibility, bioerosion, and in vivo release will be discussed. Finally, an outlook will be given for potential application fields in the future.

Keywords

  • Drug Release
  • Sustained Release
  • Release Profile
  • Direct Compression
  • Lipid Matrix

These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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  • DOI: 10.1007/978-1-4939-1417-3_12
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Correspondence to Julia Engert .

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Engert, J. (2015). Implants as Sustained Release Delivery Devices for Vaccine Antigens. In: Foged, C., Rades, T., Perrie, Y., Hook, S. (eds) Subunit Vaccine Delivery. Advances in Delivery Science and Technology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1417-3_12

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