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I.C. Hereditary Vitreo-Retinopathies

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Vitreous

Abstract

Inherited vitreoretinopathies mostly result from genetic abnormalities of types II, IX, or V/XI collagen [see chapter I.A. Vitreous proteins] and proteoglycans, [see chapters I.B. Vitreous GAGs and I.F. Vitreous biochemistry and artificial vitreous] expressed principally and collectively in the eye but also in articular and hyaline cartilage. The phenotypes can be variable but affected patients classically exhibit high degrees of congenital myopia and visual loss from retinal detachment with varying degrees of associated hearing loss, arthropathy, and orofacial abnormalities.

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  1. Vitreoretinal Service, Cambridge University NHS Foundation Trust, Addenbrooke’s Hospital, Hill Road, Cambridge, CB2 0QQ, England, UK

    Martin P. Snead MA, MD, DO, FRCS, FRCOphth

  2. Department of Pathology, University of Cambridge, Tennis Court Rd, Cambridge, CB2 1QP, UK

    Allan J. Richards PhD

  3. Cambridge University NHS Foundation Trust, Addenbrooke’s Hospital, Cambridge, England, UK

    Allan J. Richards PhD

Authors
  1. Martin P. Snead MA, MD, DO, FRCS, FRCOphth
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  2. Allan J. Richards PhD
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Correspondence to Martin P. Snead MA, MD, DO, FRCS, FRCOphth .

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Editors and Affiliations

  1. VMR Institute for Vitreous Macula Retina, Huntington Beach, California, USA

    J. Sebag

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Snead, M.P., Richards, A.J. (2014). I.C. Hereditary Vitreo-Retinopathies. In: Sebag, J. (eds) Vitreous. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-1086-1_3

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  • DOI: https://doi.org/10.1007/978-1-4939-1086-1_3

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