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T-Cell Pseudolymphoma Presenting in a Lichenoid and Nodular Pattern

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Cutaneous Hematopathology

Abstract

The T-cell pseudolymphomas represent a heterogeneous group of skin disorders both clinically and histologically that have been subdivided into distinct clinicopathological entities. We describe a group of T-cell pseudolymphomas presenting in a lichenoid and/or nodular pattern. The disorders described in this chapter include lichenoid keratosis, lichen aureus, actinic reticuloid, lymphomatoid contact dermatitis, lymphomatoid drug reactions, and solitary T-cell pseudolymphomas. For each disorder, the definition, epidemiology, pattern of infiltration, cytomorphology, immunophenotype, cytogenetics, molecular findings, clinical behavior, and differential diagnosis are included, as well as associated histopathological images. The distinction between benign pseudolymphomas and malignant lymphomas is challenging and requires complete integration of clinical, histopathological, immunophenotypic, and molecular features. This chapter aims to describe a set of lichenoid and nodular reactive T-cell pseudolymphomas to better differentiate these benign atypical lymphoid infiltrates from the malignant cutaneous lymphomas they simulate clinically and histologically.

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Trapp, K.M., Moon, S.D., Patel, M.T., Morgan, M.B. (2014). T-Cell Pseudolymphoma Presenting in a Lichenoid and Nodular Pattern. In: Cualing, H., Kadin, M., Hoang, M., Morgan, M. (eds) Cutaneous Hematopathology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-0950-6_8

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