• David BlairEmail author
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 766)


Paragonimiasis is caused by a number of species of lung flukes of the genus Paragonimus. Understanding of the taxonomy and evolution of the genus is incomplete. Paragonimiasis is primarily zoonotic in nature and occurs in many regions of East, South, and SE Asia, the Americas, and Tropical Africa. Despite likely reductions in prevalence in recent years and changes in demographic patterns of infection, around 23 million people harbor lung flukes. Paragonimiasis is acquired by eating undercooked freshwater crabs or crayfish containing metacercariae, or by eating undercooked meat of mammalian paratenic hosts. Adult worms typically encyst in pairs in the lungs, voiding their eggs into airways and eventually to the outside via sputum, or sometimes feces. However, ectopic infections can occur, in which worms occupy atypical sites in the body, commonly the brain. Interactions with the host via the immune system are not as well understood as for some other pathogenic trematodes. Diagnosis can be difficult because signs and symptoms may be vague and nonspecific, or else mimic those of conditions such as cancer and tuberculosis. Pulmonary and some other forms of paragonimiasis are easily treated using praziquantel or triclabendazole. However, surgery may be required in some cases.


Wild Boar Adult Worm Pleural Space Intradermal Test Snail Host 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.James Cook UniversityTownsvilleAustralia

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