Abstract
Puberty marks the transition of a female from childhood to adulthood. Any variations in development can be a cause of delay in puberty. Delayed puberty is technically defined as being two standard deviations above the mean age of onset of any area of development.
This chapter will focus on the evaluation of delayed puberty, discuss the most common hormonal causes for pubertal delay, and address treatment options.
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References
Cromer B. Adolescent development. In: Kliegman RM, Stanton BF, St. Geme JW, Schor NF, Berhman RE, editors. Nelsons textbook of pediatrics. 19th ed. Philadelphia: Elsevier Saunders; 2011. p. 649.
Granada C, Loveless MB. Update on adolescent gynecology. Adolesc Med State Art Rev. 2013;24(1):133–54.
Emans SJ. Delayed puberty. In: Emans SJ, Laufer MR, editors. Pediatric and adolescent gynecology. 6th ed. Philadelphia: Lippincott Williams and Wilkins; 2012. p. 125–37.
Davis A, Reindollar R. Abnormalities of female pubertal development. http://www.endotext.org/chapter/abnormalities-of-female-pubertal-development/. Accessed 12 Aug 2013.
Pozo J, Argente J. Delayed puberty in chronic illness. Best Pract Res Clin Endocrinol Metab. 2002;16(1):73–90.
Erzi J, Marques-Vidal P, Nydegger A. Impact of disease and treatments on growth and puberty of pediatric patients with inflammatory bowel disease. Digestion. 2012;85(4):308–19.
Chapter 10, Abnormal puberty and growth patterns. In: Speroff L, Glass RH, Kase N, editors. Clinical gynecologic endocrinology and infertility. 6th ed. Baltimore: Lippincott Williams and Wilkins; 1999. p. 406–7.
Matheo LM, Murray PJ. Delayed puberty. Sanfilippo JS, Lara-Torre E, Edmonds K, Templeman C. Clinical pediatric and adolescent gynecology. 1st ed. New York: Informa Healthcare USA; 2009. p. 40–61.
Fujii K, Demura S. Relationship between change in BMI with age and delayed menache in female athletes. J Physiol Anthropol Appl Human Sci. 2003;22:97–104.
Hopwood NJ. Pathogenesis and management of abnormal puberty. Spec Top Endocrinol Metab. 1985;7:175–236.
Silveira LFG, Latronico AC. Approach to the patient with hypogonadotropic hypogonadism. J Clin Endocrinol Metab. 2013;98(5):1781–8.
Rebar RW. Premature ovarian “failure” in the adolescent. Ann N Y Acad Sci. 2008;1135:138–45.
Guerrero NV, Singh RH, Manatunga A, Berry GT, Steiner RD, Elsas II LJ. Risk factors for premature ovarian failure in females with galactosemia. J Pediatr. 2000;137(6):833–41.
Nelson LM, Covington SN, Rebar RW. An update: spontaneous premature ovarian failure is not an early menopause. Fertil Steril. 2005;83:1327–32.
De Caro JJ, Dominguez C, Sherman SL. Reproductive health of adolescent girls who carry the FMR1 premutation: expected phenotype based on current knowledge of fragile x-associated primary ovarian insufficiency. Ann N Y Acad Sci. 2008;1135:99–111.
Wallace WH, Anderson RA, Irvine DS. Fertility preservation for young patients with cancer: who is at risk and what can be offered? [published erratum appears in Lancet Oncol 2005;6:922]. Lancet Oncol. 2005;6:209–18.
Johnston RJ, Wallace WH. Normal ovarian function and assessment of ovarian reserve in the survivor of childhood cancer. Pediatr Blood Cancer. 2009;53:296–302.
Green DM, Sklar CA, Boice Jr JD, Mulvihill JJ, Whitton JA, Stovall M, et al. Ovarian failure and reproductive outcomes after childhood cancer treatment: results from the Childhood Cancer Survivor Study. J Clin Oncol. 2009;27:2374–81.
Duffy C, Allen S. Medical and psychosocial aspects of fertility after cancer. Cancer J. 2009;15:27–33.
Nabhan ZM, Dimeglio LA, Qi R, Perkins SM, Eugster EA. Conjugated oral versus transdermal estrogen replacement in girls with Turner syndrome: a pilot comparative study. J Clin Endocrinol Metab. 2009;94(6):2009–14.
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De Silva, N.K. (2014). Hormonal Causes of Delayed Puberty. In: Dietrich, J. (eds) Female Puberty. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-0912-4_10
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DOI: https://doi.org/10.1007/978-1-4939-0912-4_10
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