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Pulmonary Manifestations of Sarcoidosis

Chapter

Abstract

Sarcoidosis is a multisystem disease that can cause a myriad of symptoms and clinical abnormalities. While sarcoidosis has been recognized in the modern medical literature for nearly 150 years, the cause of sarcoidosis is still unknown and the diagnosis remains one of exclusion. More than half of sarcoidosis patients have at least two organs involved, implying that diagnosis and management require a multidisciplinary approach. The prognosis of sarcoidosis is good for the majority of patients, but it is difficult to predict which ones will remit spontaneously at the outset of the disease. It does not appear that early treatment substantially influences the likelihood of spontaneous remission. Therefore, the indications for treatment fall broadly into the two categories of threats to organ function and significant impairment of the quality of life. A range of associated manifestations, such as pulmonary hypertension, mycetomas, upper airways involvement, and sleep apnea, may complicate the management of sarcoidosis.

Keywords

Pulmonary Hypertension Idiopathic Pulmonary Fibrosis Granulomatous Inflammation Cardiac Sarcoidosis Hypersensitivity Pneumonitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Respiratory Institute, Cleveland ClinicClevelandUSA

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