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Gene Therapy for HIV pp 1–8Cite as

Principles of Gene Therapy

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Part of the book series: SpringerBriefs in Biochemistry and Molecular Biology ((BRIEFSBIOCHEM))

Abstract

Gene therapy for somatic cells is defined as the insertion, removal, or manipulation of genes, for therapeutic purposes. Gene transfer can be accomplished by the insertion of naked DNA and the application of nonviral gene transfer (transfection) or viral gene transfer (transduction) methods. These methods vary widely in their gene transfer efficacy and also in the duration of expression of the transferred gene. For durable gene expression, retroviral or lentiviral gene transfer vectors are used.

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Authors and Affiliations

  1. University of California Davis, Sacramento, CA, USA

    Gerhard Bauer & Joseph S. Anderson

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  1. Gerhard Bauer
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  2. Joseph S. Anderson
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© 2014 Gerhard Bauer and Joseph S. Anderson

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Bauer, G., Anderson, J.S. (2014). Principles of Gene Therapy. In: Gene Therapy for HIV. SpringerBriefs in Biochemistry and Molecular Biology. Springer, New York, NY. https://doi.org/10.1007/978-1-4939-0434-1_1

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