Atrial Fibrillation and Heart Failure in the Aging Population

  • Pedram KazemianEmail author
  • Bodh I. Jugdutt


Atrial fibrillation (AF) is a common condition affecting more than 2.2 million Americans, and nearly ¾ of all patients with AF are over 65. It is a major risk factor for serious cardiovascular events, such as stroke, heart failure (HF) and premature death. Aging-related atrial remodelling with fibrosis, dilation and mitochondrial DNA mutations predisposes elderly patients to AF. New therapeutic modalities including novel anticoagulation medications, antiarrhythmic drugs (AADs) and catheter-based ablation (CBA) have significantly impacted our approach to management of AF and are of particular interest for the elderly although they have not been extensively studied in this group of patients.

This chapter will review the epidemiology, pathophysiology and management options for AF and discuss the role of new advances in management of AF in the elderly.


Atrial Fibrillation Atrial Fibrillation Patient Pulmonary Vein Isolation Heart Failure With Preserve Ejection Fraction Prothrombin Complex Concentrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  1. 1.Department of Cardiac ElectrophysiologyBrigham and Women’s Hospital/HarvardNewtonUSA
  2. 2.2C2 W.C. Mackenzie Health Sciences Centre, Division of Cardiology, Department of Medicine, Mazankowski Alberta Heart InstituteUniversity of Alberta and HospitalsEdmontonCanada

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