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Chios Mastic Gum and Its Food Applications

Part of the Integrating Food Science and Engineering Knowledge Into the Food Chain book series (ISEKI-Food,volume 12)

Abstract

This chapter reviews the traditional Greek product Chios Mastic Gum or Mastiha, primarily known for its distinctive flavor. This is the dried exudate of the shrub-like tree Pistacia lentiscus L. var. chia of the Anacardiaceae family, cultivated exclusively in the south of the Greek island Chios. Emphasis is given on its chemistry and physicochemical properties, health effects, antioxidant and antimicrobial properties. The preparation of traditional food products based on mastic gum or essential oil, such as chewing gum, confectionery, bakery products as well as alcoholic and nonalcoholic beverages, is also discussed.

Keywords

  • Mastic gum
  • Mastiha
  • Essential oil
  • Terpenes

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Fig. 19.1
Fig. 19.2

References

  • Aksoy A, Duran N, Koksal F (2006) In vivo and in vitro antimicrobial effects of mastic chewing gum against Streptococcus mutants and mutants streptococci. Arch Oral Biol 51(6):476–481

    CAS  CrossRef  Google Scholar 

  • Al-Habbal MJ, Al-Habbal Z, Huwez F (1984) A double-blind controlled clinical trial of mastic and placebo in the treatment of duodenal ulcer. Clin Exp Pharmacol Physiol 11(5):541–544

    CAS  CrossRef  Google Scholar 

  • Al-Said MS, Ageel AM, Parmar NS, Tariq M (1986) Evaluation of mastic, a crude drug obtained from Pistacia lentiscus for gastric and duodenal anti-ulcer activity. J Ethnopharmacol 15(3):271–278

    CAS  CrossRef  Google Scholar 

  • Andrikopoulos NK, Kaliora AC, Assimopoulou AN, Papapeorgiou VP (2003) Biological activity of some naturally occurring resins, gums and pigments against in vitro LDL oxidation. Phytother Res 17(5):501–507

    CAS  CrossRef  Google Scholar 

  • Assimopoulou AN, Papageorgiou VP (2005) GC-MS analysis of penta- and tetra-cyclic triterpenes from resins of Pistacia species. Part I. Pistacia lentiscus var. Chia. Biomed Chromatogr 19(4):285–311

    CAS  CrossRef  Google Scholar 

  • Assimopoulou AN, Zlatanos SN, Papageorgiou VP (2005) Antioxidant activity of natural resins and bioactive triterpenes in oil substrates. Food Chem 92(4):721–727

    CAS  CrossRef  Google Scholar 

  • Balan KV, Demetzos C, Prince J, Dimas K, Cladaras M (2005) Induction of apoptosis in human colon cancer HCT116 cells treated with an extract of the plant product, Chios mastic gum. In Vivo 19(1):93–102

    Google Scholar 

  • Balan KV, Prince J, Han Z, Dimas K, Cladaras M, Wyche JH, Sitaras NM, Pantazis P (2007) Antiproliferative activity and induction of apoptosis in human colon cancer cells treated in vitro with constituents of a product derived from Pistacia lentiscus L. var. chia. Phytomedicine 14(4):263–272

    Google Scholar 

  • Barton DHR, Seoane E (1956) Triterpenoids. Part XXII. The constitution and stereochemistry of masticadienonic acid. J Chem Soc 4150–4157

    Google Scholar 

  • Bebb JR, Bailey-Flitter N, Ala’Aldeen D, Atherton JC (2003) Mastic gum has no effect on Helicobacter pylori load in vivo. J Antimicrob Chemother 52(3):522–523

    CAS  CrossRef  Google Scholar 

  • Belanger JT (1998) Perillyl alcohol: applications in oncology. Altern Med Rev 3(6):448–457

    CAS  Google Scholar 

  • Colombini MP, Modugno F, Giannarelli S, Fuoco R, Matteini M (2000) GC-MS characterization of paint varnishes. Microchem J 67(1–3):385–396

    CAS  CrossRef  Google Scholar 

  • Crowell PL (1999) Prevention and therapy of cancer by dietary monoterpenes. J Nutr 129(3):S775–S778

    Google Scholar 

  • Dabos KJ, Sfika E, Vlatta LJ, Giannikopoulos G (2010a) The effect of mastic gum on Helicobacter pylori: a randomized pilot study. Phytomedicine 17(3–4):296–299

    CAS  CrossRef  Google Scholar 

  • Dabos KJ, Sfika E, Vlatta LJ, Frantzi D, Amygdalos GI, Giannikopoulos G (2010b) Is Chios mastic gum effective in the treatment of functional dyspepsia? A prospective randomised double-blind placebo controlled trial. J Ethnopharmacol 127(2):205–209

    CrossRef  Google Scholar 

  • Daferera D, Pappas C, Tarantilis PA, Polissiou M (2002) Quantitative analysis of α-pinene and β-myrcene in mastic gum oil using FT-Raman spectroscopy. Food Chem 77(4):511–515

    CAS  CrossRef  Google Scholar 

  • Dedoussis GV, Kaliora AC, Psarras S, Chiou A, Mylona A, Papadopoulos NG, Andrikopoulos NK (2004) Antiatherogenic effect of Pistacia lentiscus via GSH restoration and downregulation of CD36 mRNA expression. Atherosclerosis 174(2):293–303

    CAS  CrossRef  Google Scholar 

  • Dietemann P, Kälin M, Zumbühl S, Knochenmuss R, Wülfert S, Zenobi R (2001) A mass spectrometry and electron paramagnetic resonance study of photochemical and thermal aging of triterpenoid varnishes. Anal Chem 73(9):2087–2096

    CAS  CrossRef  Google Scholar 

  • Dietemann P, Kälin M, White R, Sudano C, Knochenmuss R, Zenobi R (2005) Chios gum mastic—freshly harvested vs. commercial resin and its implications to aging of varnishes. Z Kunsttechnol Konserv 19(1):119–130

    Google Scholar 

  • Huwez FU, Thirlwell D, Cockayne A, Ala’Aldeen DA (1998) Mastic gum kills Helicobacter pylori. N Engl J Med 339(26):1946

    CAS  CrossRef  Google Scholar 

  • Kaliora AC, Mylona A, Chiou A, Petsios DG, Andrikopoulos NK (2004) Detection and identification of simple phenolics in Pistacia lentiscus resin. J Liq Chromatogr Relat Technol 27(2):289–300

    CAS  CrossRef  Google Scholar 

  • Kaliora AC, Stathopoulou MG, Triantafillidis JK, Dedoussis GVZ, Andrikopoulos NK (2007) Chios mastic treatment of patients with active Crohn’s disease. World J Gastroenterol 13(5):748–753

    CrossRef  Google Scholar 

  • Kehayoglou A, Doxastakis G, Kiosseoglou V (1994) Compressional properties of Chios Mastic. In: Charalambous G (ed) Food Flavors, Ingredients and composition, Proceedings of the 7th International Flavor Conference Samos, Greece, 1993, Elsevier, Amsterdam, pp 429–436

    Google Scholar 

  • Kottakis F, Lamari F, Matragkou C, Zachariadis G, Karamanos N, Choli-Papadopoulou T (2008) Arabino-Galactan proteins from Pistacia lentiscus var. chia: isolation, characterization and biological function. Amino Acids 34(3):413–420

    CAS  CrossRef  Google Scholar 

  • Kottakis F, Kouzi-Koliakou K, Pendas S, Kountouras J, Choli-Papadopoulou T (2009) Effects of mastic gum Pistacia lentiscus var. Chia on innate cellular immune effectors. Eur J Gastroenterol Hepatol 21(2):143–149

    CAS  CrossRef  Google Scholar 

  • Koutsoudaki C, Krsek M, Rodger A (2005) Chemical composition and antibacterial activity of the essential oil and the gum of Pistacia lentiscus var. chia. J Agric Food Chem 53(20):7681–7685

    CAS  CrossRef  Google Scholar 

  • Liu J (2005) Oleanolic acid and ursolic acid: research perspectives. J Ethnopharmacol 100(1–2):92–94

    CAS  CrossRef  Google Scholar 

  • Loughlin MF, Ala’Aldeen DA, Jenks PJ (2003) Monotherapy with mastic does not eradicate Helicobacter pylori infection from mice. J Antimicrob Chemother 51(2):367–371

    CAS  CrossRef  Google Scholar 

  • Loutrari H, Hatziapostolou M, Skouridou V, Papadimitriou E, Roussos C (2004) Perillyl alcohol is an angiogenesis inhibitor. J Pharmacol Exp Ther 311(2):568–575

    CAS  CrossRef  Google Scholar 

  • Loutrari H, Magkouta S, Pyriochou A, Koika V, Kolisis FN, Papapetropoulos A, Roussos C (2006) Mastic oil from Pistacia lentiscus var. chia inhibits growth and survival of human K562 leukemia cells and attenuates angiogenesis. Nutr Cancer 55(1):86–93

    CAS  CrossRef  Google Scholar 

  • Magalhaes-Queiroz DM, Luzza F (2006) Epidemiology of Helicobacter pylori infection. Helicobacter 11(Suppl 1):1–5

    CrossRef  Google Scholar 

  • Magiatis P, Melliou E, Skaltsounis A, Chinou I, Mitaku S (1999) Chemical composition and antimicrobial activity of essential oils of Pistacia lentiscus var. chia. Planta Med 65(8):749–752

    CAS  CrossRef  Google Scholar 

  • Malfetrheiner P, Megraud F, O’Morain C, Bazzoli F, El-Omar E, Graham D (2007) Current concepts in the management of Helicobacter pylori infection: the Masstricht III consensus report. Gut 56(6):772–781

    CrossRef  Google Scholar 

  • Marner FJ, Freyer A, Lex J (1991) Triterpenoids from gum mastic, the resin of Pistacia lentiscus. Phytochemistry 30(11):3709–3712

    CAS  CrossRef  Google Scholar 

  • Mavrakis C, Kiosseoglou V (2008) The structural characteristics and mechanical properties of biopolymer/mastic gum microsized particles composites. Food Hydrocolloids 22(5):854–861

    CAS  CrossRef  Google Scholar 

  • Mills JS, White R (1989) The identity of the resins from the Late Bronze Age shipwreck at Ulu Burun (Kas). Archaeometry 31(1):37–44

    CAS  CrossRef  Google Scholar 

  • Monaco P, Caputo R, Palumbo G, Mangoni L (1973) Triterpenes from the galls of Pistacia lentiscus. Phytochemistry 12(10):2534–2537

    CAS  CrossRef  Google Scholar 

  • Papageorgiou V, Mellidis A, Argyriadou N (1991) The chemical composition of the essential oil of mastic gum. J Essent Oil Res 3(2):107–110

    CAS  CrossRef  Google Scholar 

  • Papageorgiou VP, Bakola-Christianopoulou MN, Apazidou KK, Psarros EE (1997) Gas-chromatographic mass spectroscopic analysis of the acidic triterpenic fraction of mastic gum. J Chromatogr A 769(2):263–273

    CAS  CrossRef  Google Scholar 

  • Paraschos S, Magiatis P, Mitakou S, Petraki K, Kalliaropoulos A, Maragkoudakis P, Mentis A, Sgouras D, Skaltsounis A (2007) In vitro and in vivo activity of Chios mastic gum extracts and constituents against Helicobacter pylori. Antimicrob Agents Chemother 51(2):551–559

    CAS  CrossRef  Google Scholar 

  • Paraskevopoulou A, Tsoukala A, Kiosseoglou V (2009) Monitoring the behaviour of mastic gum oil volatiles release from model alcoholic beverage emulsions. Effect of emulsion composition and oil droplet size. Food Hydrocoll 23(4):1139–1148

    CAS  CrossRef  Google Scholar 

  • Perikos G (1988) Masticha the daughter of Chios. Omiros, Pireaus

    Google Scholar 

  • Sawidis T, Yurukova L, Askitis T (2010) Chios mastic, a natural supplement for zinc to enhance male sexuality and prostate function. Pharm Biol 48(1):48–54

    CAS  CrossRef  Google Scholar 

  • Seoane E (1956) Further crystalline constituents of gum mastic. J Chem Soc 4158–4160

    Google Scholar 

  • Stern B, Heron C, Corr L, Serpico M, Bourriau J (2003) Compositional variations in aged and heated Pistacia resin found in late bronze age Canaanite amphorae and bowls from Amarna, Egypt. Archaeometry 45(3):457–469

    CAS  CrossRef  Google Scholar 

  • Takahashi K, Fukasava M, Motohira H, Ochiai K, Nishikawa H, Miyata T (2003) A pilot study on antiplaque effects of mastic chewing gum in the oral cavity. J Periodontol 74(4):501–505

    CrossRef  Google Scholar 

  • Talley NJ, Stanghellini V, Heading RC, Koch KL, Malagelada JR, Tytgat GNJ (1999) Functional gastroduodenal disorders. Gut 45(2):II37–II42

    Google Scholar 

  • Tassou CC, Nychas GJE (1995) Antimicrobial activity of the essential Oil of mastic Gum (Pistacia lentiscus var. chia) on gram positive and gram negative bacteria in broth and in model food system. Int Biodeter Biodegr 36(3–4):411–420

    CAS  CrossRef  Google Scholar 

  • Topitsoglou-Themeli V, Dagalis P, Lambrou DA (1984) A Chios mastiche chewing gum and oral hygiene. I. The possibility of reducing or preventing microbial plaque formation. Hell Stomatol Chron 28(3):166–170

    CAS  Google Scholar 

  • Triantafyllou A, Chaviaras N, Sergentanis TN, Protopapa E, Tsaknis J (2007) Chios mastic gum modulates serum biochemical parameters in a human population. J Ethnopharmacol 111(1):43–49

    CrossRef  Google Scholar 

  • van den Berg KJ, van der Horst J, Boon JJ, Sudmeijer OO (1998) Cis-1,4-poly-β-myrcene; the structure of the polymeric fraction of mastic resin (Pistacia lentiscus L.) elucidated. Tetrahedron Lett 39(17):2645–2648

    CrossRef  Google Scholar 

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Correspondence to Adamantini Paraskevopoulou .

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Paraskevopoulou, A., Kiosseoglou, V. (2016). Chios Mastic Gum and Its Food Applications. In: Kristbergsson, K., Ötles, S. (eds) Functional Properties of Traditional Foods. Integrating Food Science and Engineering Knowledge Into the Food Chain, vol 12. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-7662-8_19

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