Structural-Based Models of Ventricular Myocardium

  • Lik Chuan Lee
  • Jonathan Wenk
  • Doron Klepach
  • Ghassan S. KassabEmail author
  • Julius M. Guccione


Ventricular wall stress is an important determinant of myocardial oxygenconsumption (Sarnoff et~al. 1958; Strauer et~al. 1977), ventricular remodeling, and hypertrophy (Grossman 1980), and is necessary for an understanding of both physiological and pathological ventricular mechanics (Yin 1981). Despite recent advancement in measurement techniques and computational modeling, a detailed knowledge of ventricular wall stress (particularly in patients diagnosed with heart disease) remains elusive.


Constitutive Model Collagen Fiber Strain Energy Function Biaxial Testing Left Ventricle Wall 
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Copyright information

© Springer Science+Business Media, LLC 2016

Authors and Affiliations

  • Lik Chuan Lee
    • 1
  • Jonathan Wenk
    • 2
  • Doron Klepach
    • 3
  • Ghassan S. Kassab
    • 4
    Email author
  • Julius M. Guccione
    • 5
  1. 1.Department of Mechanical EngineeringMichigan State UniversityEast LansingUSA
  2. 2.Department of Mechanical Engineering and SurgeryUniversity of KentuckyLexingtonUSA
  3. 3.Department of Mechanical or Industrial Engineering, AltairTel Aviv University, Multiscale Design Systems, LLC, UCSF, UC Berkeley, University of CaliforniaBerkeleyUSA
  4. 4.California Medical Innovations InstituteSan DiegoUSA
  5. 5.Department of SurgeryUniversity of California at San FranciscoSan FranciscoUSA

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