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Genetic Counseling for Adult Neurogenetic Disease pp 239–249Cite as

The Myopathies

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Abstract

The myopathies are non-dystrophic conditions in which the muscle does not function properly. This chapter focuses on some common adult-onset myopathies, including myofibrillar myopathy, distal myopathy, and metabolic myopathy. Myofibrillar myopathies present with slowly progressive muscle weakness of distal greater than proximal muscles. The distal myopathies are a heterogeneous group of disorders that predominantly affect the distal muscles. The metabolic myopathies are a heterogeneous group of inherited conditions with exercise intolerance and rhabdomyolysis leading to progressive muscle weakness, chronic pain, and fatigue.

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Author information

Authors and Affiliations

  1. Paul and Sheila Wellstone Muscular Dystrophy Center, University of Minnesota, 2101 6th St. SE MC, Minneapolis, MN, 55455, USA

    Joline Dalton

  2. Taub Institute, Columbia University Medical Center, 630 W. 168th St., Box 16, New York, NY, 10032, USA

    Jill S. Goldman

  3. Department of Neurology, Columbia University Medical Center, 630 W. 168th St., Box 16, New York, NY, 10032, USA

    Jacinda B. Sampson

Authors
  1. Joline Dalton
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  2. Jill S. Goldman
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  3. Jacinda B. Sampson
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Corresponding author

Correspondence to Joline Dalton .

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Editors and Affiliations

  1. Taub Institute, Columbia University Medical Center, New York, New York, USA

    Jill S. Goldman

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© 2015 Springer Science+Business Media New York

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Dalton, J., Goldman, J.S., Sampson, J.B. (2015). The Myopathies. In: Goldman, J. (eds) Genetic Counseling for Adult Neurogenetic Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-7482-2_19

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