Abstract
A bone marrow trephine biopsy and a bone marrow aspirate give complementary information. Cytological detail is usually better in films of an aspirate whereas bone marrow architecture can be assessed only on a trephine biopsy specimen. In addition, trephine biopsies can demonstrate focal lesions which may be missed by aspiration. They are essential in conditions such as myelofibrosis when an aspirate cannot be obtained.
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© 1997 Paola Domizio and David Lowe
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Bain, B.J. (1997). Bone marrow. In: Domizio, P., Lowe, D. (eds) Reporting Histopathology Sections. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-7132-6_17
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DOI: https://doi.org/10.1007/978-1-4899-7132-6_17
Publisher Name: Springer, Boston, MA
Print ISBN: 978-0-412-43040-4
Online ISBN: 978-1-4899-7132-6
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