The cortex of the anterior pole of the brain can be subdivided, histologically and physiologically, into three major parts. They have been most clearly identified and extensively investigated in the frontal lobe of the primate: (1) the primary motor cortex, a strip of agranular cortex rostral and adjacent to the central sulcus; (2) the premotor cortex, a conglomerate of cytoarchitectonically transitional areas, including the supplementary motor area (SMA); and (3) the prefrontal cortex, which constitutes the largest and most anterior of the three components and which, in the primate at least, has a prominent internal granular layer (IV) and for this reason is known as the granular frontal cortex. The three components can be well distinguished in the external convexity of the frontal lobe; in the cingulate and inferior (orbital) aspects of the lobe, the first two components are absent and the granular cytoarchitecture of the prefrontal cortex blends more or less gradually into that of limbic cortex behind it.


Frontal Cortex Supplementary Motor Area Dorsolateral Prefrontal Cortex Premotor Cortex Contingent Negative Variation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

Further reading

  1. Fuster JM (1980): The Prefrontal Cortex. New York: Raven Press.Google Scholar
  2. Fuster JM (1981): Prefrontal cortex in motor control. In: Handbook of Physiology, Nervous System, Vol II: Motor Control, pp 1149–1178, Brooks VB, ed. Bethesda: American Physiological Society.Google Scholar
  3. Fuster JM (1984): Behavioral electrophysiology of the prefrontal cortex. Trend Neurosci 7: 408–414.CrossRefGoogle Scholar
  4. Rosenkilde CE (1979): Functional heterogeneity of the prefrontal cortex in the monkey: A review. Behav Neurol Biol 25: 301–345.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Joaquin M. Fuster

There are no affiliations available

Personalised recommendations