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Alzheimer Therapy with Cholinomimetics: The Japanese Experience

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Cholinergic Basis for Alzheimer Therapy

Part of the book series: Advances in Alzheimer Disease Therapy ((AADT))

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Abstract

There are various drugs which are used to improve functions of the brain disturbed by stroke or senile dementia of Alzheimer type (SDAT) in Japan. Usually they are divided into two groups by the different mechanisms of action (Otomo, 1989). One group acts mainly on the vascular system of the brain; i.e., increasing blood flow of the brain, promoting antiplatelet coagulation or lowering blood viscosity. The drugs in this group are nicardipine, ifenprodil, pentoxifylline, dilazep, trapidil, vinpocetine, moxisylate, brovincamine, nicergoline and cinepazide. The other group acts directly on the brain; i.e., as neurotransmitters or activators of energy metabolism. These include dihydroergotoxine, Ca hopantenate, idebenone, bifemelane, amantadine, tiapride and indeloxazine.

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© 1991 Springer Science+Business Media New York

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Yoshida, M. (1991). Alzheimer Therapy with Cholinomimetics: The Japanese Experience. In: Becker, R., Giacobini, E. (eds) Cholinergic Basis for Alzheimer Therapy. Advances in Alzheimer Disease Therapy. Birkhäuser, Boston, MA. https://doi.org/10.1007/978-1-4899-6738-1_36

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  • DOI: https://doi.org/10.1007/978-1-4899-6738-1_36

  • Publisher Name: Birkhäuser, Boston, MA

  • Print ISBN: 978-1-4899-6740-4

  • Online ISBN: 978-1-4899-6738-1

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