Genetically Defined Myelin Disorders

  • Ravina Simons
  • John R. Riordan


Myelin is a multilayered membranous sheath characteristic of nervous tissue. It insulates the axons of selected neurons along their entire length in discrete segments, increasing the conduction velocity of electrical nerve impulses traveling down these axons. The myelin is interrupted by bare patches of axon called nodes. Each myelinated segment is known as an internode. Myelin occurs in vertebrate nervous systems in two main forms, central and peripheral. It also occurs in some invertebrates in a form that resembles the myelin found in the peripheral nervous system (PNS) of vertebrates (Raine, 1984a).


Schwann Cell Myelin Basic Protein Myelin Sheath Myelin Protein Proteolipid Protein 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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© Springer Science+Business Media New York 1992

Authors and Affiliations

  • Ravina Simons
  • John R. Riordan

There are no affiliations available

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