Skip to main content
SpringerLink
Log in
Book cover

Techniques of Neurolysis pp 87–94Cite as

Epidural Fibrosis: Experimental Model and Therapeutic Alternatives

  • Chapter

Part of the book series: Current Management of Pain ((CUMP,volume 4))

Abstract

Lumbosacral disorders are currently the leading cause of disability in people under 45 years of age, thus causing a monumental problem to society, to the patient, and to the physician [1]. Part of the problem is that much remains to be learned and understood concerning the varied causes and the basis for appropriate management of this type of pain patient.

This is a preview of subscription content, log in via an institution.

Chapter
USD   29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD   169.00
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever

Tax calculation will be finalised at checkout

Purchases are for personal use only

Learn about institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. Kelsey JL, White AA. 1980. Epidemiology and impact of low-back pain. Spine 5. 133–142.

    Article  PubMed  CAS  Google Scholar 

  2. LaRocca H, Macnab I. 1974. The laminectomy membrane: Studies in its evolution, characteristics, effects and prophylaxis in dogs. J Bone Joint Surg 5613. 545–550.

    Google Scholar 

  3. McCarron RF, Wimpee M, Hudkins P, Laros GS. 1987. The inflammatory effect of nucleus pulposus. Spine 12. Accepted for publication.

    Google Scholar 

  4. Racz GB, Sabonghy M, Guintaulas J, Kline WM. 1982. Intractable pain therapy using a new epidural catheter. JAMA 248. 579–581.

    Article  PubMed  CAS  Google Scholar 

  5. Heavner JE. 1984. Personal communication.

    Google Scholar 

  6. Wahl SM, Wahl LM. 1981. Modulation of fibroblast growth and function by monokines and lymphokines. In Pick E (ed): Lymphokines. New York, Academic Press. 179–201.

    Google Scholar 

  7. Postlethwaite AE et al. 1982. Formation of multinucleated giant cells from human monocyte precursors. Mediation by a soluble protein from antigen- and mitogen-stimulated lymphycytes. J Exp Med 155. 168.

    Article  PubMed  CAS  Google Scholar 

  8. Ryan GB, Spector WG. 1970. Macrophage turnover in inflamed connective tissue. Proc R Soc Lond Biol 174. 269.

    Article  PubMed  CAS  Google Scholar 

  9. Boros DL. 1978. Granulomatous inflammation. Prog Allergy 24. 184.

    Google Scholar 

  10. Crock HV. 1983. Practice of Spinal Surgery. Vienna, Springer-Verlag.

    Book  Google Scholar 

  11. Akeson WH, Woo SL, Taylor TKF, Ghosh P, Bushell GR. 1977. Biomechanics and biochemistry of the intervertebral disk. Clin Orthop 129. 133–140.

    PubMed  CAS  Google Scholar 

  12. Braun IF, Lin JR, Benjamin MU, Kriecheff II. 1984. Computed tomography of the asymptomatic postsurgical lumbar spine: analysis of the physiologic scar. AJR 142. 149–152.

    Article  PubMed  CAS  Google Scholar 

  13. Halperin N, Agasi M, Hendel D. 1982. Painless root compression following disc extrusion. Arch Orthop Trauma Surg 101. 63–66.

    Article  PubMed  CAS  Google Scholar 

  14. Gerbstein SD, Tyle M, Gross A. 1975. Autoimmunity in degenerative disc disease of the lumbar spine. Orthop Clin North Am 6. 67.

    Google Scholar 

  15. Kelly M. 1956. Is pain due to pressure of nerves? Neurology 6. 32–36.

    Article  PubMed  CAS  Google Scholar 

  16. Marshall LL, Trethewie ER, Curtain CC. 1977. Chemical radiculitis. Clin Orthop 129. 61–67.

    PubMed  Google Scholar 

  17. Marshall L, Trethewie ER. 1973. Chemical irritation of nerve-root in disc prolapse. Lancet 2. 320.

    Article  PubMed  CAS  Google Scholar 

  18. Smyth MJ, Wright V. 1958. Sciatica and the intervertebral disc. J Bone Joint Surg 40A. 1401–1418.

    PubMed  Google Scholar 

  19. Kirkaldy-Willis WH. 1984. The relationship of structural pathology to the nerve root. Spine 9. 49–52.

    Article  PubMed  CAS  Google Scholar 

  20. Fernstrom U. 1960. Discographical study of ruptured lumbar intervertebral discs. Acta Chir Scand Suppl 258.

    Google Scholar 

  21. Fernstrom U. 1960. Disk rupture with surgical observations. Acta Chir Scand Suppl 258.

    Google Scholar 

  22. Lipson SJ, Muir H. 1981. Proteoglycans in experimental intervertebral disc degeneration. Spine 6. 194–210.

    Article  PubMed  CAS  Google Scholar 

  23. Macnab I. 1971. In Hirsch C, Zoherman Y: The Mechanism of Spondylogenic Pain in Cervical Pain. Oxford, Pergamon Press. 89–95.

    Google Scholar 

  24. McCulloch JA, Macnab I. 1983. Sciatica and Chymopapain. Baltimore, Williams and Wilkins. 191–195.

    Google Scholar 

  25. Schneidemann G et al. 1987. Magnetic resonance in the diagnosis of disc degeneration: correlation with discography. Spine 12. 276–281.

    Article  Google Scholar 

  26. Hoffman GS. 1983. Spinal arachnoiditis I and II. Spine 8. 538–551.

    Article  PubMed  CAS  Google Scholar 

  27. Wilkinson HA, Schuman N. 1979. Results of surgical lysis of lumbar arachnoiditis. Neurosurgery 4. 401–409.

    Article  PubMed  CAS  Google Scholar 

  28. Crock HV. 1983. Personal communication.

    Google Scholar 

  29. Kivilvoto OP. 1976. Use of free fat transplants to prevent epidural scar formation. Acta Orthop Scan (Suppl) 164.

    Google Scholar 

  30. Mikiwa Y et al. 1986. an experimental study on prevention of post laminectomy scar formation by the use of new materials. Spine 11. 843–846.

    Article  Google Scholar 

Download references

Authors
  1. Robert F. McCarron
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Gabor B. Racz

Rights and permissions

Reprints and permissions

Copyright information

© 1989 Springer Science+Business Media New York

About this chapter

Cite this chapter

McCarron, R.F. (1989). Epidural Fibrosis: Experimental Model and Therapeutic Alternatives. In: Racz, G.B. (eds) Techniques of Neurolysis. Current Management of Pain, vol 4. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-6721-3_8

Download citation

  • DOI: https://doi.org/10.1007/978-1-4899-6721-3_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-1-4899-6723-7

  • Online ISBN: 978-1-4899-6721-3

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation