The structure of nucleoproteins1–5 is of importance because, in the cell nucleus, DNA is almost completely complexed with protein and the transference of genetic information from the DNA to RNA, and hence to the synthetic mechanisms, is likely to be profoundly modified by the presence of the protein. The existence of this complex in a stable form appears to be essential to the structure of the chromosome since agents which dissociate the complex also disrupt the structure of the chromosome. After the early interest in the protein component, attention was largely directed to the DNA, but, in recent years, the nuclear proteins and the nature of their complex with DNA have again been the subject of study. The nature of the interaction of the RNA-protein complex of ribosomes is largely unknown.
KeywordsPhosphorus Hydrate Sodium Chloride Lysine Polypeptide
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