Abstract
During electron-probe analysis of asbestos bodies and anthracotic pigment in tissue sections of human lung, X-ray spectrometer scans for most elements of the periodic table yielded an unexpected result. Titanium was found in high local concentrations associated with some asbestos bodies and not others; and, as expected, iron, silicon, and magnesium were also present. Further examination of both lung and hilar lymph node tissue showed that some particles with the usual light microscopic appearance of anthracotic pigment also contained titanium. The association and proportions of titanium, iron, and silicon in particles in the lung and hilar lymph nodes was not constant. An individual with lung and hilar lymph nodes containing high titanium had worked as a painter. Titanium dioxide paint pigment might have been the source in this particular case.
Work supported by National Institutes of Health Contract No. PH-43-67-104.
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Banfield, W.G., Tousimis, A.J., Hagerty, J.C., Padden, T.R. (1969). Electron Probe Analysis of Human Lung Tissues. In: Earle, K.M., Tousimis, A.J. (eds) X-Ray and Electron Probe Analysis in Biomedical Research. Progress in Analytical Chemistry. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-5907-2_2
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DOI: https://doi.org/10.1007/978-1-4899-5907-2_2
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