Abstract
The respiratory muscles are the only skeletal muscles whose regular contraction is necessary for the maintenance of life. In this respect their role is intermediate between that of other skeletal muscles and cardiac muscle. Their action may be altered profoundly in patients with COPD. In such individuals dysfunction of the respiratory muscles can have major effects on the maintenance of ventilation awake and asleep and during exercise, on the motion of the chest and abdomen, on pulmonary gas exchange and the symptom of dyspnea. The importance of abnormalities of muscle function in patients with COPD has been appreciated increasingly over the last 20 years as a result of many studies in all these areas.
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Gibson, G.J. (1995). Respiratory Muscles. In: Calverley, P.M.A., Pride, N.B. (eds) Chronic Obstructive Pulmonary Disease. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-4525-9_9
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