The volatile nitrites, such as amyl nitrite, are liquids which are inhaled and have been used in medical practice since the mid-1800s in the treatment of angina pectoris. Prior to 1968, these substances were available without prescription. After 1968, these substances were also used as room odorizers and as such could be obtained without prescription. These products are marketed under several different trade names which indicate the intent for which they are actually sold, e.g., Heart On, Aroma of Men, Rush. These products come in fragile 10–30 ml bottles (“poppers”) which are easily “popped” or “snapped” so that the contents can be inhaled.
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