Leukodiapedesis, Compartmentalisation and Secretion of PMN Leukocyte Proteinases, and Activation of PMN Leukocyte Procollagenase

  • H. Tschesche
  • B. Bakowski
  • A. Schettler
  • V. Knäuper
  • H. Reinke
  • S. Krämer
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 297)


Human polymorphonuclear leukocytes (PMNL) are the first phagocytic cells to arrive at the site of injury of the epithelium, where they regulate the defense reactions against invading microorganisms. Therefore, their accumulation characterises an inflammatory process. Some particular properties of PMNL (Fig. 1) such as phagocytising microorganisms and eliminating damaged tissue are described [1].


Basement Membrane Human Neutrophil Partial Amino Acid Sequence Specific Granule Complete Primary Structure 
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Copyright information

© Springer Science+Business Media New York 1991

Authors and Affiliations

  • H. Tschesche
    • 1
  • B. Bakowski
    • 1
  • A. Schettler
    • 1
  • V. Knäuper
    • 1
  • H. Reinke
    • 1
  • S. Krämer
    • 1
  1. 1.Fakultät für ChemieUniversität BielefeldBielefeld 1Germany

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