Cocaine, Benzoylecgonine and Ecgonine Methyl Ester Determinations in Post Mortem Human Urine and Blood by Gas Chromatography and Capillary Gas Chromatography after “Extrelut®” Extraction

  • R. Froldi
  • V. Gambaro
  • A. Groppi


Blood and urine level determinations of cacaine and its metabolites are important for the correct toxicological evaluation of “death due to cocaine”. In fact the significance of the biological fluid concentration in fatal cases can be assessed from human clinical studies1–3. On the other hand the urine and blood concentrations provide toxicological data that may assist forensic toxicologist and pathologist in the interpretation of the time and also the manner of death. The concentration of cocaine and its metabolites in body tissues is less important for the death investigation from the medico legal point of view4–9.


Toxicity Ethyl Transportation Chloroform Acetonitrile 


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Copyright information

© Springer Science+Business Media New York 1987

Authors and Affiliations

  • R. Froldi
    • 1
  • V. Gambaro
    • 2
  • A. Groppi
    • 3
  1. 1.Institute of Forensic MedicineUniversity of MacerataMacerataItaly
  2. 2.University of MilanMilanItaly
  3. 3.University of PaviaPaviaItaly

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