Cocaine, Benzoylecgonine and Ecgonine Methyl Ester Determinations in Post Mortem Human Urine and Blood by Gas Chromatography and Capillary Gas Chromatography after “Extrelut®” Extraction
Blood and urine level determinations of cacaine and its metabolites are important for the correct toxicological evaluation of “death due to cocaine”. In fact the significance of the biological fluid concentration in fatal cases can be assessed from human clinical studies1–3. On the other hand the urine and blood concentrations provide toxicological data that may assist forensic toxicologist and pathologist in the interpretation of the time and also the manner of death. The concentration of cocaine and its metabolites in body tissues is less important for the death investigation from the medico legal point of view4–9.
KeywordsToxicity Ethyl Transportation Chloroform Acetonitrile
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- 2.H.E. Hamilton, J.E. Wallace, E.L. Shimek, P. Land, S.C. Harris and J.G. Christenson, Cocaine and benzoylecgonine excretion in humans, J. Forens. Sci. 22: 697 (1977).Google Scholar
- 4.B.S. Finkle and K.L. McCloskey, The forensic toxicology of cocaine (1971–1976), J. Forens. Sci. 23: 173 (1978).Google Scholar
- 8.C.V. Wetli and R.E. Mittleman, The “body packer syndrome”. Toxicity following ingestion of illicit drugs packaged for transportation, J. Forens. Sci. 26: 492 (1981).Google Scholar