Sterol Metabolism in Aspergillus Species

  • Michael A. Gealt
  • Brian E. Shapiro
  • Theresa A. Lindley
  • Joseph L. Evans


The functional complexity of the eukaryotic membrane requires a similar structural complexity. One of the major components of the membrane is the sterol molecule, such as cholesterol (in animals), sitosterol (in plants), and ergosterol (in fungi). These neutral lipid molecules act not only as a bulk lipid, but also act to stabilize the fluidity of the membrane structure, thus allowing for protein function under conditions such as high or low temperature under which the phospholipid hydrocarbon chains might either gel or become too fluid for proper physiological functioning.


High Performance Liquid Chromatography Aspergillus Nidulans Sterol Ester Free Sterol Steryl Ester 
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Copyright information

© Springer Science+Business Media New York 1988

Authors and Affiliations

  • Michael A. Gealt
    • 1
  • Brian E. Shapiro
    • 1
    • 2
  • Theresa A. Lindley
    • 1
    • 3
  • Joseph L. Evans
    • 1
    • 4
  1. 1.Department of Bioscience and BiotechnologyDrexel UniversityPhiladelphiaUSA
  2. 2.Dept. of AnesthesiologyHahnemann University HospitalPhiladelphiaUSA
  3. 3.Dept. of MicrobiologyMedical College of PennsylvaniaPhiladelphiaUSA
  4. 4.Dept. of MedicineDartmouth University School of MedicineHanoverUSA

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