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Prophylaxis and Treatment of Pneumocystis Carinii Pneumonia

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AIDS and Respiratory Medicine

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Abstract

Pneumocystis carinii pneumonia (PCP) was the firstly widely reported major opportunistic infection of the AIDS epidemic (Gottblieb et al., 1981). Its importance has never diminished and it has remained one of the commonest AIDS events in the developed world (Hoover et al., 1993). The recognition that it is an early and (with prophylaxis) often avoidable AIDS illness has promoted an increased interest in its presentation and management. The improved survival times that are now seen following an episode of PCP have accounted almost exclusively for the increase in overall AIDS survival (Jacobson et al., 1993). The prophylaxis and treatment of PCP is therefore a vital part of current HIV management. This chapter addresses drug therapy as it applies to clinical practice. It also covers management strategies and ventilatory support; it concludes with a discussion of factors that predict clinical outcome.

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Authors
  1. Marc C. I. Lipman
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  2. Margaret A. Johnson
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Editor information

Editors and Affiliations

  1. Department of Medicine, University College London Medical School, London, UK

    Alimuddin Zumla BSc MB ChB MSc PhD FRCP (Director, Visiting Professor, Honorary Consultant in Infectious Diseases) (Director, Visiting Professor, Honorary Consultant in Infectious Diseases)

  2. Camden and Islington Community Health Services NHS Trust, London, UK

    Alimuddin Zumla BSc MB ChB MSc PhD FRCP (Director, Visiting Professor, Honorary Consultant in Infectious Diseases) (Director, Visiting Professor, Honorary Consultant in Infectious Diseases)

  3. Department of Medicine, University of Zambia School of Medicine, Lusaka, Zambia

    Alimuddin Zumla BSc MB ChB MSc PhD FRCP (Director, Visiting Professor, Honorary Consultant in Infectious Diseases) (Director, Visiting Professor, Honorary Consultant in Infectious Diseases)

  4. Department of Respiratory Medicine, The Royal Free Hospital, London, UK

    Margaret Johnson MD, FRCP (Consultant Physician) (Consultant Physician)

  5. Department of Sexually Transmitted Diseases, Division of Pathology and Infectious Diseases, University College London Medical School, London, UK

    Robert Miller MB FRCP (Senior Lecturer/Honorary Consultant Physician, Honorary Consultant Physician) (Senior Lecturer/Honorary Consultant Physician, Honorary Consultant Physician)

  6. Camden and Islington Community Health Services NHS Trust, London, UK

    Robert Miller MB FRCP (Senior Lecturer/Honorary Consultant Physician, Honorary Consultant Physician) (Senior Lecturer/Honorary Consultant Physician, Honorary Consultant Physician)

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© 1997 Springer Science+Business Media Dordrecht

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Lipman, M.C.I., Johnson, M.A. (1997). Prophylaxis and Treatment of Pneumocystis Carinii Pneumonia. In: Zumla, A., Johnson, M., Miller, R. (eds) AIDS and Respiratory Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3446-8_7

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  • DOI: https://doi.org/10.1007/978-1-4899-3446-8_7

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-412-60140-8

  • Online ISBN: 978-1-4899-3446-8

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