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Mechanisms of Neutrophil Mediated Injury

  • Chapter
ARDS Acute Respiratory Distress in Adults

Abstract

The morphologic appearance of the lung in the syndrome of acute respiratory distress in adults (ARDS), in which extensive neutrophil accumulation is seen in all compartments (Chapter 4), defines this syndrome as reflecting an overwhelming inflammatory process. In the context of apparent injury to epithelial and endothelial surfaces, a model for the pathogenesis of ARDS suggests that injury by inflammatory cells plays a central role (Chapter 5).

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Authors
  1. G. Scott Worthen
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  2. Gregory P. Downey
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Editor information

Editors and Affiliations

  1. National Heart & Lung Institute, USA

    Timothy W. Evans MD, FRCP, PhD (Reader in Critical Care Medicine, Consultant in Thoracic and Intensive Care Medicine) (Reader in Critical Care Medicine, Consultant in Thoracic and Intensive Care Medicine)

  2. Royal Brompton Hospital, Sydney Street, London, SW3 6NP, UK

    Timothy W. Evans MD, FRCP, PhD (Reader in Critical Care Medicine, Consultant in Thoracic and Intensive Care Medicine) (Reader in Critical Care Medicine, Consultant in Thoracic and Intensive Care Medicine)

  3. University of Edinburgh, Royal Infirmary, Lauriston Place, Edinburgh, EH3 9YW, UK

    Christopher Haslett FRCP, FRCP (Edin) (Professor of Respiratory Medicine, Chairman of the Department of Medicine (RIE) and Director of the Rayne Laboratories) (Professor of Respiratory Medicine, Chairman of the Department of Medicine (RIE) and Director of the Rayne Laboratories)

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© 1996 Springer Science+Business Media Dordrecht

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Worthen, G.S., Downey, G.P. (1996). Mechanisms of Neutrophil Mediated Injury. In: Evans, T.W., Haslett, C. (eds) ARDS Acute Respiratory Distress in Adults. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3430-7_8

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  • DOI: https://doi.org/10.1007/978-1-4899-3430-7_8

  • Publisher Name: Springer, Boston, MA

  • Print ISBN: 978-0-412-56910-4

  • Online ISBN: 978-1-4899-3430-7

  • eBook Packages: Springer Book Archive

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