Diet and breast cancer

  • Maureen Hunter
  • Clare Shaw


There is an increasing amount of evidence to suggest that diet may play a role in the aetiology of cancer and it is estimated that an average of 35% of all cancers may be attributable to diet (Bingham, 1990). The possible association between diet and breast cancer has been the subject of particular attention, interest and research. Early experiments showed that high fat diets were an effective means of promoting tumour growth in animals with chemically-induced mammary tumours. Total energy intake also appeared to influence tumour growth, with high energy intakes causing tumour promotion. The effects of fat and energy intakes appear to be separate (Schatzkin et al., 1989).


Breast Cancer Total Energy Intake Medroxyprogesterone Acetate Eating Difficulty Nutritional Care 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Bingham, S. (1990) Diet and Cancer Briefing Paper, Health Education Authority and Department of Health, London.Google Scholar
  2. Boyar, A.P., Rose, D.P., Loughridge, J.R. et al. (1988) Response to a diet low in total fat in women with postmenopausal breast cancer: a pilot study. Nutr. Cancer, 11(2), 93–9.PubMedCrossRefGoogle Scholar
  3. Boyd, N.F., Cousins, M., Lockwood, G. and Tritchler, D. (1990) The feasibility of testing experimentally the dietary fat-breast cancer hypothesis. Prog. Clin. Biol Res., 346, 231–41.PubMedGoogle Scholar
  4. Boyle, P. and Leake, R. (1988) Progress in understanding breast cancer: epidemiology and biological interactions. Breast Cancer Research and Treatment, 11, 91–112.PubMedCrossRefGoogle Scholar
  5. Clodius, L. (1977) Secondary Arm Lymphoedema, in (1977) Lymphoedema (ed. L. Clodius), Thienne, Stuttgart, p. 151.Google Scholar
  6. de Waard, F., Baanders-van Halewijn, E.A. and Huizinga, J. (1964) The bimodal age distribution of patients with mammary carcinoma. Cancer, 17, 141–51.CrossRefGoogle Scholar
  7. de Waard, E., Ramlau, R., Mulders, Y. et al. (1993) A feasibility study on weight reduction in obese postmenopausal breast cancer patients. Eur. J. of Cancer Prev., 2, 233–8.CrossRefGoogle Scholar
  8. Harvey, E.B., Schairer, C., Brinton, L.A. et al. (1987) Alcohol consumption and breast cancer. Journal of the National Cancer Institute, 28(4), 657–61.Google Scholar
  9. Hiatt, R.A. (1990) Alcohol consumption and breast cancer. Medical Oncology and Tumour Pharmacotherapy, 7(213), 143–51.Google Scholar
  10. Hirayama, T. (1978) Epidemiology of breast cancer with special reference to the role of diet. Preventative Medicine, 7, 173–95.CrossRefGoogle Scholar
  11. Ingram, D., Nottage, E. Ng, S. et al. (1989) Obesity and breast disease, the role of female sex hormones. Cancer, 64, 1049–53.PubMedCrossRefGoogle Scholar
  12. Kelsey, J.L., Fischer, D.B., Holford, T.R. et al. (1981) Exogenous oestrogens and other factors in epidemiology of breast cancer. NHCI, 67, 327–33.Google Scholar
  13. Lubin, F., Ruder, A.M., Wax, Y. and Modan, B. (1985) Overweight and changes in weight throughout adult life in breast cancer aetiology. Am. J. Epid., 122, 579–88.Google Scholar
  14. MacDonald, I. (1948) Resection of the axillary vein in radical mastectomy: its relation to the mechanism of lymphoedema. Cancer, November, 618–22.Google Scholar
  15. Medical Research Council Scottish Trials Office (1987) Adjuvant tamoxifen in the management of operable breast cancer; the Scottish trial. Lancet, 25 July, 171–5.Google Scholar
  16. Mirabile, V., Placucci, P., Mazzoleni, C. et al. (1992) Preliminary results of diet- therapy. Progress in Lymphology, XIII, 559–60, Ed. R.V. Cluzan, A.P. Pecking, F.M. Lokiec, Pub. Excerpta Medica, London.Google Scholar
  17. National Advisory Committee on Nutrition Education (1983) Proposals for Nutritional Guidelines for Health Education in Britain, Health Education Council, London.Google Scholar
  18. Powles, T.J., Hardy, J.R., Ashley, S.E. et al. (1989) A pilot trial to evaluate the acute toxicity and feasibility of tamoxifen for prevention of breast cancer. British Journal of Cancer, 60, 126–31.PubMedCrossRefGoogle Scholar
  19. Prentice, R.L., Kakar, F., Hursting, S. et al. (1988) Aspects for the rationale for the Women’s Health Trial. Journal of the National Cancer Institute, 80(11), 802–14.PubMedCrossRefGoogle Scholar
  20. Rose, D.P. (1986) Dietary factors and breast cancer. Cancer Surveys, 5(3), 671–87.PubMedGoogle Scholar
  21. Rose, D.P. and Connolly, J.M. (1990) Dietary prevention of breast cancer. Med. Oncology and Tumour Pharmacotherapy, 1, 121–30.Google Scholar
  22. Schatzkin, A., Greenwald, P., Byar, D.P. and Clifford, C.K. (1989) The dietary fat-breast cancer hypothesis is alive. Journal of the American Medical Association, 261(22), 3284–7.PubMedCrossRefGoogle Scholar
  23. Sedlacek, S.M. (1988) An overview of megestrol acetate for the treatment of advanced breast cancer. Seminars in Oncology, 15, 2nd supplement, 3–13.PubMedGoogle Scholar
  24. Senie, R.T., Rosen, P.P., Rhodes, P. et al. (1992) Obesity at diagnosis of breast carcinoma influences duration of disease free survival. Annals of Internal Medicine, 116, 26–32.PubMedCrossRefGoogle Scholar
  25. Shils, M. (1979) Principles of nutritional therapy. Cancer, 43, 2093–2102.PubMedCrossRefGoogle Scholar
  26. Treves, N. (1957) An evaluation of etiological factors of lymphedema following radical mastectomy. Cancer, 10, 444–59.PubMedCrossRefGoogle Scholar
  27. von Meyenfeldt, M.F., Fredix, E.W.H.M., Haagh, W.A.J.J.M. et al. (1988) The aetiology and management of weight loss and malnutrition in cancer patients. Bailliere’s Clinical Gastroenterology, Volume 2, Part 4, 869–85, Bailliere Tindall, London.CrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media Dordrecht 1996

Authors and Affiliations

  • Maureen Hunter
  • Clare Shaw

There are no affiliations available

Personalised recommendations