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Bone scanning

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Clinical Nuclear Medicine

Abstract

The isotope bone scan was only performed on a limited scale prior to 1972, but since the introduction of the 99mTc-labelled phosphate and diphosphonate compounds (Subramanian et al., 1972; Castronovo, 1972) the value of this investigation in clinical practice has become increasingly recognized and it is now the most important and frequently requested study in any nuclear medicine department. Nowadays the bone scan is almost exclusively performed with 99mTc-labelled diphosphonate (methylene diphosphonate being the most popular) and the technique shows exquisite sensitivity for the detection of skeletal abnormality. However, there is the major limitation that scan appearances are non-specific. Nevertheless, in many clinical situations recognizable patterns of bone scan abnormality may be seen, which can often suggest a specific diagnosis. In this chapter, the current status of bone scanning in metastatic and benign skeletal disease will be discussed.

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  1. I. Fogelman
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Editors and Affiliations

  1. Guy’s Hospital, London, UK

    M. N. Maisey

  2. St Bartholomew’s Hospital, London, UK

    K. E. Britton

  3. The Hospital for Sick Children, Toronto, Canada

    D. L. Gilday

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Fogelman, I. (1991). Bone scanning. In: Maisey, M.N., Britton, K.E., Gilday, D.L. (eds) Clinical Nuclear Medicine. Springer, Boston, MA. https://doi.org/10.1007/978-1-4899-3358-4_6

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